Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated
with abnormal inflammatory immune responses of the lung to noxious particles and gases. …

Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of
the airways and progressive destruction of lung parenchyma, a process that in most cases is …

A Task Force supported by the European Respiratory Society was set up in 1997 in order to
address the major issues relevant to difficult/therapy-resistant asthma. Although the group of …

The methodology for EPOS2012 has been the same as for the other two productions. Leaders
in the field were invited to critically appraise the literature and write a report on a subject …

Background Patients with severe asthma are at increased risk of exacerbations and lower
respiratory tract infections (LRTI). Severe asthma is heterogeneous, encompassing …

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway
inflammation. It is unclear if dendritic cells (DC) participate in this inflammatory process. …

The term severe refractory asthma (SRA) in adults applies to patients who remain difficult to
control despite extensive re-evaluation of diagnosis and management following an …

T helper 2 (Th2)-like cytokines are thought to play a crucial role in the pathogenesis of airway
inflammation in atopic asthma, leading to bronchial hyperresponsiveness. To investigate …

Cigarette smoke (CS), the primary risk factor of chronic obstructive pulmonary disease (COPD),
leads to pulmonary inflammation through interleukin-1 receptor (IL-1R)I signalling, as …

The Belgian severe asthma registry is a web-based registry encompassing demographic,
clinical, functional and inflammatory data of severe asthmatics (SA), aiming at improving …