User profiles for Guido Haenen

Guido Haenen

Maastricht University
Verified email at maastrichtuniversity.nl
Cited by 26868

Health effects of quercetin: from antioxidant to nutraceutical

AW Boots, GRMM Haenen, A Bast - European journal of pharmacology, 2008 - Elsevier
Quercetin, a member of the flavonoids family, is one of the most prominent dietary antioxidants.
It is ubiquitously present in foods including vegetables, fruit, tea and wine as well as …

Oxidants and antioxidants: state of the art

A Bast, GRMM Haenen, CJA Doelman - The American journal of medicine, 1991 - Elsevier
Reactive oxygen species are regarded as merely pernicious. This is incorrect for they play a
pivotal role in many physiologic reactions, such as cytochrome P450-mediated oxidations, …

The pharmacology of the antioxidant lipoic acid

GP Biewenga, GRMM Haenen, A Bast - General Pharmacology: The …, 1997 - Elsevier
1. Lipoic acid is an example of an existing drug whose therapeutic effect has been related to
its antioxidant activity. 2. 2. Antioxidant activity is a relative concept: it depends on the kind …

Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures

R van den Berg, GRMM Haenen, H van den Berg… - Food chemistry, 1999 - Elsevier
The TEAC (Trolox equivalent antioxidant capacity) assay is based on scavenging of 2,2′-azinobis-(3-
ethylbenzothiazoline-6-sulfonate) radical anions (ABTS − ). In this report we …

Interactions between flavonoids and proteins: effect on the total antioxidant capacity

MJTJ Arts, GRMM Haenen, LC Wilms… - Journal of agricultural …, 2002 - ACS Publications
Flavonoids are potent antioxidants. It is also known that flavonoids bind to proteins. The
effect of the interaction between tea flavonoids and proteins on the antioxidant capacity was …

Peroxynitrite scavenging by flavonoids

GRMM Haenen, JBG Paquay, REM Korthouwer… - Biochemical and …, 1997 - Elsevier
The peroxynitrite scavenging activity of a series of structurally related flavonoids was tested.
It was found that flavonoids are excellent scavengers of peroxynitrite. Compared to the …

Flavonoids as scavengers of nitric oxide radical

SABE Vanacker, MNJL Tromp, GRMM Haenen… - Biochemical and …, 1995 - Elsevier
Flavonoids are a group of naturally occurring compounds used, eg, in the treatment of vascular
endothelial damage. They are known to be excellent scavengers of oxygen free radicals. …

The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids

BM Rezk, GRMM Haenen, WJF van der Vijgh… - … and biophysical research …, 2002 - Elsevier
Phloretin is a dihydrochalcone flavonoid that displays a potent antioxidant activity in peroxynitrite
scavenging and the inhibition of lipid peroxidation. Comparison with structurally related …

Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay

MJTJ Arts, GRMM Haenen, HP Voss, A Bast - Food and Chemical …, 2004 - Elsevier
The Trolox Equivalent Antioxidant Capacity (TEAC) assay is based on the scavenging of the
2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical (ABTS • ) converting …

[PDF][PDF] Biomarkers

…, A Collins, M Cooke, S Coolen, G Haenen… - Molecular aspects of …, 2002 - academia.edu
The earliest work on oxidation of a biologically important protein was on the effects of selected
radicals generated by radiolysis on the enzyme, lysozyme (Adams et al., 1969). Both the …