Uterine artery remodeling and reproductive performance are impaired in endothelial nitric oxide synthase-deficient mice

OWH van der Heijden, YPG Essers, G Fazzi… - Biology of …, 2005 - academic.oup.com
The progressive rise in uterine blood flow during pregnancy is accompanied by outward
hypertrophic remodeling of the uterine artery (UA). This process involves changes of the arterial …

[PDF][PDF] Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context

…, JMH Karel, E Wijnands, BSR Claes, GE Fazzi… - Cell metabolism, 2022 - cell.com
Cells often adopt different phenotypes, dictated by tissue-specific or local signals such as
cell-cell and cell-matrix contacts or molecular micro-environment. This holds in extremis for …

Integrative multiomics analysis of human atherosclerosis reveals a serum response factor‐driven network associated with intraplaque hemorrhage

…, O Waring, K van Kuijk, GE Fazzi… - Clinical and …, 2021 - Wiley Online Library
Background While single‐omics analyses on human atherosclerotic plaque have been very
useful to map stage‐ or disease‐related differences in expression, they only partly capture …

[HTML][HTML] Epstein-Barr virus and mismatch repair deficiency status differ between oesophageal and gastric cancer: A large multi-centre study

…, A Hoelscher, E Bollschweiler, GE Fazzi… - European journal of …, 2018 - Elsevier
Background Oesophageal (OeC) and gastric (GC) cancer patients are treated with similar
multimodal therapy and have poor survival. There remains an urgent clinical need to identify …

Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis

…, IM Garrelds, JGR De Mey, G Fazzi… - European …, 2015 - Eur Respiratory Soc
Limited literature sources implicate mast-cell mediator chymase in the pathologies of pulmonary
hypertension and pulmonary fibrosis. However, there is no evidence on the contribution …

Pollination of Specklinia by nectar-feeding Drosophila: the first reported case of a deceptive syndrome employing aggregation pheromones in Orchidaceae

…, D Grimaldi, KK Beentjes, R Butôt, GE Fazzi… - Annals of …, 2015 - academic.oup.com
Background and Aims The first documented observation of pollination in Pleurothallidinae
was that of Endrés, who noticed that the ‘viscid sepals’ of Specklinia endotrachys were visited …

Expression of proteins associated with the Warburg‐effect and survival in colorectal cancer

…, CCJM Simons, I Samarska, GE Fazzi… - The Journal of …, 2022 - Wiley Online Library
Previous research has suggested that the expression of proteins related to the Warburg effect
may have prognostic value in colorectal cancer (CRC), but results remain inconsistent. Our …

Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial

…, V Vromen, Y Janssen, N Davarzani, GE Fazzi… - British Journal of …, 2023 - nature.com
Background Only a subset of gastric cancer (GC) patients with stage II–III benefits from
chemotherapy after surgery. Tumour infiltrating lymphocytes per area (TIL density) has been …

Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery

…, K Poesen, D Lambrechts, GMJ Janssen, GE Fazzi… - Circulation, 2010 - Am Heart Assoc
Background— Control of peripheral resistance arteries by autonomic nerves is essential for
the regulation of blood flow. The signals responsible for the maintenance of vascular …

High sodium intake increases blood pressure and alters renal function in intrauterine growth–retarded rats

MW Sanders, GE Fazzi, GMJ Janssen, CE Blanco… - …, 2005 - Am Heart Assoc
A suboptimal fetal environment increases the risk to develop cardiovascular disease in the
adult. We reported previously that intrauterine stress in response to reduced uteroplacental …