Background Tibolone is a synthetic steroid used for the treatment of menopausal symptoms,
on the basis of short‐term data suggesting its efficacy. We considered the balance between …

Objectives To test the hypothesis that a multifaceted, local public campaign could be feasible
and influence antibiotic prescribing for outpatients. Design Community level, controlled, non…

Background Professional setting might be a key determinant of physicians' attitudes toward
practice guidelines, influencing the effect of their implementation. Because no previous …

Purpose Whether inhaled medications improve long‐term survival in Chronic Obstructive
Pulmonary Disease (COPD) is an open question. The purpose of this study is to assess the …

Background The Informed Health Choices (IHC) project team developed learning resources
for primary school children to teach critical thinking about treatments claims and health …

Objectives Investigating end-of-life use of anticancer drugs and of palliative care services.
Design Population based cohort linked to mortality registry and administrative databases. …

The implementation of public health knowledge is a complex process; researchers focus on
organizational barriers but generally give little attention to the format and validity of relevant …

Background The wide offer of information on pharmaceuticals does not often fulfill physicians’
needs: problems of relevance, access, quality and applicability are widely recognized, and …

Inhaled corticosteroid (ICS) use in chronic obstructive pulmonary disease (COPD) patients
is associated with a reduction of exacerbations and a potential risk of pneumonia. The …

Combined inhaled therapy in chronic obstructive pulmonary disease (COPD) is commonly
used, but its benefits remain controversial. We assessed the effect of tiotropium in reducing …