User profiles for Gisele Padilha

Gisele de A. Padilha Cavalcanti de Albuquerque

Professora, Faculdade de Medicina de Petrópolis/UNIFASE
Verified email at prof.unifase-rj.edu.br
Cited by 319

[HTML][HTML] Bosutinib therapy ameliorates lung inflammation and fibrosis in experimental silicosis

PJ Carneiro, AL Clevelario, GA Padilha… - Frontiers in …, 2017 - frontiersin.org
Silicosis is an occupational lung disease for which no effective therapy exists. We hypothesized
that bosutinib, a tyrosine kinase inhibitor, might ameliorate inflammatory responses, …

[HTML][HTML] Respiratory and systemic effects of LASSBio596 plus surfactant in experimental acute respiratory distress syndrome

…, CS Samary, CC Araujo, GA Padilha… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Exogenous surfactant has been proposed as adjunctive therapy for acute
respiratory distress syndrome (ARDS), but it is inactivated by different factors present in the …

[HTML][HTML] Characterization of a mouse model of emphysema induced by multiple instillations of low-dose elastase

MV Oliveira, SC Abreu, GA Padilha, NN Rocha… - Frontiers in …, 2016 - frontiersin.org
Many experimental models have been proposed to study the pathophysiological features of
emphysema, as well as to search for new therapeutic approaches for acute or chronically …

Effects of pressure support ventilation on ventilator-induced lung injury in mild acute respiratory distress syndrome depend on level of positive end-expiratory pressure …

PAF Magalhaes, GA Padilha, L Moraes… - European Journal of …, 2018 - journals.lww.com
BACKGROUND Harmful effects of spontaneous breathing have been shown in experimental
severe acute respiratory distress syndrome (ARDS). However, in the clinical setting, …

Static and Dynamic Transpulmonary Driving Pressures Affect Lung and Diaphragm Injury during Pressure-controlled versus Pressure-support Ventilation in …

…, RS Santos, MA Antunes, LA Maia, GA Padilha… - …, 2020 - pubs.asahq.org
Editor’s Perspective What We Already Know about This Topic Both pressure-support and
pressure-controlled ventilation may be used in patients with acute respiratory distress …

[HTML][HTML] Ghrelin therapy improves lung and cardiovascular function in experimental emphysema

…, CL Braga, G Guimaraes, LA Maia, GA Padilha… - Respiratory …, 2017 - Springer
Background Emphysema is a progressive disease characterized by irreversible airspace
enlargement followed by a decline in lung function. It also causes extrapulmonary effects, such …

[HTML][HTML] Effects of crystalloid, hyper-oncotic albumin, and iso-oncotic albumin on lung and kidney damage in experimental acute lung injury

RS Mendes, MV Oliveira, GA Padilha, NN Rocha… - Respiratory …, 2019 - Springer
Background Conflicting data have reported beneficial effects of crystalloids, hyper-oncotic
albumin (20%ALB), and iso-oncotic albumin (5%ALB) in critically ill patients. Although hyper-…

[HTML][HTML] Therapeutic effects of LASSBio-596 in an elastase-induced mouse model of emphysema

GA Padilha, I Henriques, M Lopes-Pacheco… - Frontiers in …, 2015 - frontiersin.org
Emphysema is an intractable pulmonary disease characterized by an inflammatory process
of the airways and lung parenchyma and ongoing remodeling process in an attempt to …

[HTML][HTML] Variability in tidal volume affects lung and cardiovascular function differentially in a rat model of experimental emphysema

CGRS Wierzchon, G Padilha, NN Rocha… - Frontiers in …, 2017 - frontiersin.org
In experimental elastase-induced emphysema, mechanical ventilation with variable tidal
volumes (V T ) set to 30% coefficient of variation (CV) may result in more homogenous …

[HTML][HTML] Impact of positive biphasic pressure during low and high inspiratory efforts in Pseudomonas aeruginosa-induced pneumonia

DG da Cruz, RF de Magalhaes, GA Padilha… - PloS one, 2021 - journals.plos.org
Background During pneumonia, normal alveolar areas coexist adjacently with consolidated
areas, and high inspiratory efforts may predispose to lung damage. To date, no study has …