[HTML][HTML] The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55

J Kargl, N Balenga, GP Parzmair, AJ Brown… - Journal of Biological …, 2012 - ASBMB
The G protein-coupled receptor (GPCR) 55 (GPR55) and the cannabinoid receptor 1 (CB1R)
are co-expressed in many tissues, predominantly in the central nervous system. Seven …

VPM1002 as prophylaxis against severe respiratory tract infections including coronavirus disease 2019 in the elderly: a phase 3 randomized, double-blind, placebo …

…, S Brückner, M May, GP Parzmair… - Clinical Infectious …, 2023 - academic.oup.com
Background Bacille Calmette-Guérin (BCG) vaccination can potentially reduce the rate of
respiratory infections in vulnerable populations. This study evaluates the safety and efficacy of …

Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking

…, A Theiler, S Philipose, GP Parzmair… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: Increased vascular permeability is a fundamental characteristic of inflammation.
Substances that are released during inflammation, such as prostaglandin (PG) E 2 , …

Results of the phase I open label clinical trial SAKK 06/14 assessing safety of intravesical instillation of VPM1002BC, a recombinant mycobacterium Bacillus Calmette …

…, H Püschel, G Wirth, R Cathomas, GP Parzmair… - …, 2020 - Taylor & Francis
Full article: Results of the phase I open label clinical trial SAKK 06/14 assessing safety of
intravesical instillation of VPM1002BC, a recombinant mycobacterium Bacillus Calmette Guérin …

Opposing roles of prostaglandin D2 receptors in ulcerative colitis

…, GP Parzmair, C Högenauer, P Kump… - The Journal of …, 2014 - journals.aai.org
Proresolution functions were reported for PGD 2 in colitis, but the role of its two receptors, D-type
prostanoid (DP) and, in particular, chemoattractant receptor homologous molecule …

The G‐protein coupled receptor associated sorting protein GASP‐1 regulates the signalling and trafficking of the viral chemokine receptor US28

…, E Moser, D Thompson, HF Vischer, GP Parzmair… - Traffic, 2010 - Wiley Online Library
Human cytomegalovirus (HCMV) encodes the seven transmembrane (7TM)/G‐protein
coupled receptor (GPCR) US28, which signals and endocytoses in a constitutive, ligand‐…

ADAP plays a pivotal role in CD4+ T cell activation but is only marginally involved in CD8+ T cell activation, differentiation, and immunity to pathogens

GP Parzmair, M Gereke, O Haberkorn… - Journal of Leucocyte …, 2017 - academic.oup.com
The adhesion and degranulation promoting adaptor protein (ADAP) is a multifunctional scaffold
involved in many different signaling pathways that are important for the function of T cells…

[HTML][HTML] ADAP Promotes Degranulation and Migration of NK Cells Primed During in vivo Listeria monocytogenes Infection in Mice

…, M Van Ham, M Heyner, M Voss, GP Parzmair… - Frontiers in …, 2020 - frontiersin.org
The adhesion and degranulation-promoting adaptor protein (ADAP) serves as a multifunctional
scaffold and is involved in the formation of immune signaling complexes. To date only …

Phosphoinositide‐dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils

EM Sturm, GP Parzmair, B Radnai… - European journal of …, 2015 - Wiley Online Library
Prostaglandin E 2 (PGE 2 ) protects against allergic responses via binding to prostanoid
receptor EP4, which inhibits eosinophil migration in a PI3K/PKC‐dependent fashion. The …

[HTML][HTML] Enhanced Susceptibility of ADAP-Deficient Mice to Listeria monocytogenes Infection Is Associated With an Altered Phagocyte Phenotype and Function

MAL Böning, GP Parzmair, A Jeron… - Frontiers in …, 2021 - frontiersin.org
The adhesion and degranulation-promoting adaptor protein (ADAP) serves as a multifunctional
scaffold and is involved in the formation of immune signaling complexes. To date, only …