User profiles for Gavin C. Donaldson

Gavin Donaldson

Professor, NHLI, Imperial College
Verified email at imperial.ac.uk
Cited by 33086

Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease

TAR Seemungal, GC Donaldson, EA Paul… - American journal of …, 1998 - atsjournals.org
Exacerbations occur commonly in patients with moderate or severe chronic obstructive
pulmonary disease (COPD) but factors affecting their severity and frequency or effects on quality …

Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease

TAR Seemungal, GC Donaldson… - American journal of …, 2000 - atsjournals.org
Although exacerbations of chronic obstructive pulmonary disease (COPD) are associated
with symptomatic and physiological deterioration, little is known of the time course and …

Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease

TMA Wilkinson, GC Donaldson, JR Hurst… - American journal of …, 2004 - atsjournals.org
Treatment of chronic obstructive pulmonary disease (COPD) exacerbations improves
outcomes; however, responses to treatment are variable, and patients with COPD often delay …

Increased risk of myocardial infarction and stroke following exacerbation of COPD

GC Donaldson, JR Hurst, CJ Smith, RB Hubbard… - Chest, 2010 - Elsevier
Objective Patients with COPD are at risk for cardiovascular events. This is attributed to
increased systemic inflammation. The course of COPD is punctuated by exacerbations, which …

Airway and systemic inflammation and decline in lung function in patients with COPD

GC Donaldson, TAR Seemungal, IS Patel, A Bhowmik… - Chest, 2005 - Elsevier
Study objectives Patients with COPD experience lower airway and systemic inflammation,
and an accelerated decline in FEV 1 . There is no evidence on whether this inflammation …

Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease

JR Hurst, GC Donaldson, WR Perera… - American journal of …, 2006 - atsjournals.org
Impact: This study explores the use of measuring plasma biomarkers at exacerbation of
chronic obstructive pulmonary disease (COPD), providing insight into the underlying …

Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fibrinogen and serum IL-6 levels

…, EA Paul, GC Donaldson… - Thrombosis and …, 2000 - thieme-connect.com
Respiratory tract infections may acutely increase risk from coronary heart disease (CHD),
though the mechanisms have not been defined. Patients with chronic obstructive pulmonary …

Heat related mortality in warm and cold regions of Europe: observational study

WR Keatinge, GC Donaldson, E Cordioli, M Martinelli… - Bmj, 2000 - bmj.com
… We calculated the average mortality at successive 3C temperature bands at increments
of 0.1C to determine the 3C band of lowest mortality in each region. For each region, daily …

Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease

…, SJ Lloyd-Owen, GC Donaldson… - American journal of …, 2004 - atsjournals.org
Relationships between high-resolution computed tomography (HRCT) findings in chronic
obstructive pulmonary disease (COPD) and bacterial colonization, airway inflammation, or …

Inflammatory changes, recovery and recurrence at COPD exacerbation

…, H Müllerova, GC Donaldson… - European …, 2007 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) exacerbations are associated with increased
airway and systemic inflammation, though relationships between exacerbation recovery, …