User profiles for Gary C. Sieck
Gary SieckMayo Clinic Verified email at Mayo.edu Cited by 22696 |
Altered diaphragm contractile properties with controlled mechanical ventilation
…, VJ Caiozzo, A Manka, GC Sieck - Journal of applied …, 2002 - journals.physiology.org
This study shows that, over time, diaphragm inactivity with controlled mechanical ventilation
(CMV) decreases diaphragm force and produces myofibril damage contributing to the …
(CMV) decreases diaphragm force and produces myofibril damage contributing to the …
Oxidative capacity of human muscle fiber types: effects of age and training status
…, WE Sinning, JM Walro, GC Sieck… - Journal of applied …, 1995 - journals.physiology.org
Morphometry and oxidative capacity of slow-twitch (type I) and fast-twitch (type IIa and IIb)
muscle fibers obtained from vastus lateralis needle biopsies were compared between younger …
muscle fibers obtained from vastus lateralis needle biopsies were compared between younger …
Diaphragm dysfunction in chronic obstructive pulmonary disease
CAC Ottenheijm, LMA Heunks, GC Sieck… - American journal of …, 2005 - atsjournals.org
Rationale: Hypercapnic respiratory failure because of inspiratory muscle weakness is the most
important cause of death in chronic obstructive pulmonary disease (COPD). However, the …
important cause of death in chronic obstructive pulmonary disease (COPD). However, the …
Effects of voluntary activity and genetic selection on aerobic capacity in house mice (Mus domesticus)
… Carter, Wen-Zhi Zhan, and Gary C. Sieck. Effects of voluntary activity and genetic selection
… and wood shavings in a temperature-controlled room (∼22C) with a constant 12:12-h light-…
… and wood shavings in a temperature-controlled room (∼22C) with a constant 12:12-h light-…
Diaphragm motor unit recruitment during ventilatory and nonventilatory behaviors
GC Sieck, M Fournier - Journal of Applied Physiology, 1989 - journals.physiology.org
The forces generated by the cat diaphragm (DIA) during different ventilatory and nonventilatory
behaviors were determined by measuring transdiaphragmatic pressures (Pdi). The Pdi …
behaviors were determined by measuring transdiaphragmatic pressures (Pdi). The Pdi …
Pressure-time product during continuous positive airway pressure, pressure support ventilation, and T-piece during weaning from mechanical ventilation
The objective of this study was to compare the effects of continuous positive airway pressure
(CPAP), pressure support ventilation (PS), and T. plece on the pressure-time product (PTP) …
(CPAP), pressure support ventilation (PS), and T. plece on the pressure-time product (PTP) …
[HTML][HTML] 1α, 25-Dihydroxyvitamin D3 regulates mitochondrial oxygen consumption and dynamics in human skeletal muscle cells
Muscle weakness and myopathy are observed in vitamin D deficiency and chronic renal
failure, where concentrations of the active vitamin D 3 metabolite, 1α,25-dihydroxyvitamin D 3 (…
failure, where concentrations of the active vitamin D 3 metabolite, 1α,25-dihydroxyvitamin D 3 (…
Mitochondrial dysfunction in airway disease
YS Prakash, CM Pabelick, GC Sieck - Chest, 2017 - Elsevier
There is increasing appreciation that mitochondria serve cellular functions beyond oxygen
sensing and energy production. Accordingly, it has become important to explore …
sensing and energy production. Accordingly, it has become important to explore …
Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle
…, M Thompson, R Vassallo, GC Sieck… - … of Physiology-Lung …, 2014 - journals.physiology.org
The balance between mitochondrial fission and fusion is crucial for mitochondria to perform
its normal cellular functions. We hypothesized that cigarette smoke (CS) disrupts this …
its normal cellular functions. We hypothesized that cigarette smoke (CS) disrupts this …
Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers
…, MJ Cody, RL Macken, GC Sieck - Journal of applied …, 2000 - journals.physiology.org
In the present study, myosin heavy chain (MHC) content per half sarcomere, an estimate of
the number of cross bridges available for force generation, was determined in rat diaphragm …
the number of cross bridges available for force generation, was determined in rat diaphragm …