A consensus document for the selection of lung transplant candidates: 2014—an update from the Pulmonary Transplantation Council of the International Society for …

…, LG Singer, GI Snell, GM Verleden… - The Journal of Heart and …, 2015 - Elsevier
The appropriate selection of lung transplant recipients is an important determinant of outcomes.
This consensus document is an update of the recipient selection guidelines published in …

Azithromycin: mechanisms of action and their relevance for clinical applications

…, G Perletti, GM Verleden… - Pharmacology & …, 2014 - Elsevier
Azithromycin is a macrolide antibiotic which inhibits bacterial protein synthesis, quorum-sensing
and reduces the formation of biofilm. Accumulating effectively in cells, particularly …

An official American Thoracic Society/European Respiratory Society statement: research questions in chronic obstructive pulmonary disease

…, DP Tashkin, T Troosters, GM Verleden… - American journal of …, 2015 - atsjournals.org
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity,
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…

Humoral immunity in phenotypes of chronic lung allograft dysfunction: a broncho-alveolar lavage fluid analysis

…, G Opdenakker, GM Verleden… - Transplant …, 2016 - Elsevier
Background Recently, antibody mediated rejection (AMR) has been associated with a
higher incidence of chronic lung allograft dysfunction (CLAD) and mortality after lung …

Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT

GM Verleden, AR Glanville, ED Lease… - The Journal of Heart …, 2019 - jhltonline.org
The outcomes of transplantation vary widely by organ. Lung transplantation (LTx) has rather
poor long-term outcome, with a current median post-transplant survival of 6.0 years. 1, 2 …

A new classification system for chronic lung allograft dysfunction

GM Verleden, G Raghu, KC Meyer, AR Glanville… - The Journal of Heart and …, 2014 - Elsevier
Although survival after lung transplantation has improved significantly during the last decade,
chronic rejection is thought to be the major cause of late mortality. The physiologic …

An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome

KC Meyer, G Raghu, GM Verleden, PA Corris, P Aurora… - 2014 - Eur Respiratory Soc
Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that
is associated with poor survival. The International Society for Heart and Lung Transplantation…

Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease

…, D Testelmans, GM Verleden… - American journal of …, 2007 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway
inflammation. It is unclear if dendritic cells (DC) participate in this inflammatory process. …

Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome

GM Verleden, BM Vanaudenaerde… - American journal of …, 2006 - atsjournals.org
… Williams TJ, Verleden GM. Azithromycin: a plea for multicenter randomized studies in lung …
Correspondence and requests for reprints should be addressed to Professor GM Verleden, Ph…

The pathogenesis of pulmonary fibrosis: a moving target

…, AU Wells, GM Verleden - European …, 2013 - Eur Respiratory Soc
Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is
characterised by excessive matrix formation leading to destruction of the normal lung architecture …