Throughout the biological world, a 30 Å hydrophobic film typically delimits the environments
that serve as the margin between life and death for individual cells. Biochemical and …

One of the challenges of contemporary cell biology is to unravel how the molecular composition
of the different cellular compartments is generated and maintainedduring the cell cycle. …

The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a
polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The …

To assess the potential role of interleukin-6 (IL-6) in the pathogenesis of dengue virus
infection, levels of this cytokine were measured in children with dengue virus infection on …

… (G.van Meer, unpublishedresults). As a consequence, a plaque titration ofthe virus on MDCK
strain I cells does not require trypsin. Whenthe surface of MDCK strain I cells was treated …

Technological developments, especially in mass spectrometry and bioinformatics, have
revealed that living cells contain thousands rather than dozens of different lipids [for …

Lipids are produced, transported, and recognized by the concerted actions of numerous
enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, "…

In 2005, the International Lipid Classification and Nomenclature Committee under the
sponsorship of the LIPID MAPS Consortium developed and established a "Comprehensive …

The human MDR1 P-glycoprotein (Pgp) extrudes a variety of drugs across the plasma
membrane. The homologous MDR3 Pgp is required for phosphatidylcholine secretion into bile. …

Lysosomal storage disorders, of which more than 40 are known, are caused by the
defective activity of lysosomal proteins, which results in the intra-lysosomal accumulation of …