… Chemokines are small cytokines signaling via a G-protein coupled seven transmembrane
receptors and attracting cells bearing the respective receptor type. In sarcoidosis a variety of …

… Pechkovsky DV, Prasse A, Ludwig C, Goebel H, Mueller-Quernheim J, Zissel G. CCL18
expression and production by human alveolar macrophages in co-culture with lung fibroblasts […

BIBF 1000 is a small molecule inhibitor targeting the receptor kinases of platelet-derived
growth factor (PDGF), basic fibroblast growth factor and vascular endothelial growth factor, …

… antigenic target of 6 kD) and KatG (catalase-peroxidase G).[27] It has been shown that
recognition … [44] Zissel et al provided a more detailed discussion on cytokines in sarcoidosis.[45] …

… In the larger group of sarcoidosis patients without LS, the most significantly associated
haplotype 4 included the complementary allele rs2076530 G and was under-represented in cases…

… Prasse A, Pechkovsky DV, Toews GB, Jungraithmayer W, Kollert F, Goldmann T, Vollmer
E, Müller-Quernheim J, Zissel G. A vicious circle of alveolar macrophages and fibroblasts …

Activated macrophages have been characterized as M1 and M2 according to their inflammatory
response pattern. Here we analyzed the M2 marker expression and intracellular signal …

… In addition, the percentage of CCL18-positive alveolar macrophages (G) and the relative …
Values in G and H are presented as box plots, where the boxes represent the 25th to 75th …

At the time of diagnosis, many sarcoidosis patients have no clinical indication for corticosteroid
therapy, and prognostic parameters predicting deterioration are missing. In the present …

… toxin-sensitive G i/o and pertussis toxin-insensitive Gα 15 proteins (12, 13). The G protein-…
5-HTR 6 and 5-HTR 7 are linked to G s protein-mediated stimulation of adenylyl cyclase (22…