Hydroxyapatite (HA) enriched with strontium and boron ions was synthesized using two
different methods: the precipitation method (Sr,B-HAw) and the dry method (Sr,B-HAd). …

Individuals with impaired immune responses, such as ventilated and cystic fibrosis patients
are often infected with Pseudomonas aeruginosa (Pa) bacteria, and a co-infection with the …

Chronic obstructive pulmonary disease and emphysema are associated with increased elastin
peptides (EP) production because of excessive breakdown of lung connective tissue. We …

Background In chronic obstructive pulmonary disease (COPD), lung-infiltrating inflammatory
cells secrete proteases and participate in elastin breakdown and genesis of elastin-derived …

Mutations in the gene encoding the chloride ion channel CFTR (cystic fibrosis transmembrane
conductance regulator) result in cystic fibrosis (CF), the most common lethal autosomal …

Deterioration of lung functions and degradation of elastin fibers with age are accelerated
during chronic obstructive pulmonary disease (COPD). Excessive genesis of soluble elastin …

Introduction Cystic Fibrosis (CF) is the commonest genetically inherited disease (1 in 4,500
newborns) and 70% of people with CF (pwCF) harbour the F508Del mutation, resulting in …

Staphylococcus aureus is one of the most frequently involved pathogens in bacterial
infections such as skin abscess, pneumonia, endocarditis, osteomyelitis, and implant-associated …

Background As part of their role in immune response and inflammation, monocytes exhibit a
potent procoagulant phenotype which is mediated by Tissue Factor (TF), the main trigger of …

… Mechiche Alami 1* , Flora Lemaire 1 , Jerome M. Josse 2* , Pierre Schaaf 3* , Stéphanie
Sayen 4* , Sophie S. Gangloff 2* , Fréderic Velard 1 , Joseph Hemmerlé 3* , Dominique …