The role of short-chain fatty acids, produced by anaerobic bacteria, in the cystic fibrosis airway

…, AA Azim, C Gunaratnam, F Healy… - American journal of …, 2015 - atsjournals.org
Rationale: Anaerobic bacteria are present in large numbers in the airways of people with
cystic fibrosis (PWCF). In the gut, anaerobes produce short-chain fatty acids (SCFAs) that …

The importance of Ras in drug resistance in cancer

FM Healy, IA Prior, DJ MacEwan - British Journal of …, 2022 - Wiley Online Library
In this review, we analyse the impact of oncogenic Ras mutations in mediating cancer drug
resistance and the progress made in the abrogation of this resistance, through …

[HTML][HTML] Worked to the bone: antibody-based conditioning as the future of transplant biology

JM Griffin, FM Healy, LN Dahal, Y Floisand… - Journal of Hematology & …, 2022 - Springer
Conditioning of the bone marrow prior to haematopoietic stem cell transplant is essential in
eradicating the primary cause of disease, facilitating donor cell engraftment and avoiding …

Lung function over the first 3 years of life in children with congenital diaphragmatic hernia

…, DJ Weiner, R Feng, MR Perez, F Healy… - Pediatric …, 2015 - Wiley Online Library
Objectives Infants with congenital diaphragmatic hernia (CDH) have variable degrees of
pulmonary hypoplasia at birth. Few reports of lung function over the first years of life exist in this …

[HTML][HTML] Recent progress in interferon therapy for myeloid malignancies

FM Healy, LN Dahal, JRE Jones, Y Floisand… - Frontiers in …, 2021 - frontiersin.org
Myeloid malignancies are a heterogeneous group of clonal haematopoietic disorders, caused
by abnormalities in haematopoietic stem cells (HSCs) and myeloid progenitor cells that …

[HTML][HTML] Unexpected genetic heterogeneity for primary ciliary dyskinesia in the Irish Traveller population

JP Casey, PA McGettigan, F Healy, C Hogg… - European Journal of …, 2015 - nature.com
We present a study of five children from three unrelated Irish Traveller families presenting
with primary ciliary dyskinesia (PCD). As previously characterized disorders in the Irish …

Clinical practice: the impact of lung disease on the heart and cardiac disease on the lungs

F Healy, BD Hanna, R Zinman - European journal of pediatrics, 2010 - Springer
Pathologies in both the respiratory and cardiovascular systems frequently coexist and impact
on each other. This manuscript introduces an approach to the interpretation of this complex …

[HTML][HTML] The natural history of cystic fibrosis liver disease a prospective cohort study

…, F Emer, C Gallagher, G Peter, G Cedric, H Fiona… - Journal of Cystic …, 2023 - Elsevier
Background Our understanding of the natural history of cystic fibrosis liver disease (CFLD)
is limited, leading to uncertainty for patients their families and clinicians when liver …

Tracheostomy decision making: from placement to decannulation

F Flanagan, F Healy - Seminars in Fetal and Neonatal Medicine, 2019 - Elsevier
… Author links open overlay panel Frances Flanagan a , Fiona Healy b … Fiona Healy has
no relevant conflict of interest or funding sources to declare. …

Pulmonary complications of pediatric neurological diseases

F Healy, HB Panitch - Pediatric annals, 2010 - journals.healio.com
CME EDUCATIONAL OBJECTIVES 1. Outline the pathophysiology of the respiratory
complications associated with neurological disease in children. 2. List the treatment options for …