Hypersensitivity reactions to aspirin (acetylsalicylic acid) and other nonsteroidal anti‐inflammatory
drugs ( NSAID s) constitute only a subset of all adverse reactions to these drugs, but …

Background Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity
and mortality worldwide, and accurate estimates of the prevalence of this disease are …

NSAID ‐exacerbated respiratory disease (N‐ ERD ) is a chronic eosinophilic, inflammatory
disorder of the respiratory tract occurring in patients with asthma and/or chronic rhinosinusitis …

Background Never smokers comprise a substantial proportion of patients with COPD. Their
characteristics and possible risk factors in this population are not yet well defined. Methods …

Background Chronic obstructive pulmonary disease (COPD) is a commonly reported cause
of death and associated with smoking. However, COPD mortality is high in poor countries …

Aspirin intolerance and the cyclooxygenase–leukotriene pathw... : Current Opinion in Pulmonary
Medicine Aspirin intolerance and the cyclooxygenase–leukotriene pathways : Current Opinion in …

Background Numerous open trials have demonstrated the beneficial clinical effects of aspirin
desensitization (AD) in patients with aspirin-induced asthma (AIA). These beneficial effects …

Chronic rhinosinusitis ( CRS ) is a multifactorial disease of the upper airways with a high
prevalence (approximately 11%) in the general population. Different immune and inflammatory …

We studied the prevalence, burden and potential risk factors for chronic bronchitis
symptoms in the Burden of Obstructive Lung Disease study. Representative population-based …

Rationale: The Global Burden of Disease program identified smoking and ambient and
household air pollution as the main drivers of death and disability from chronic obstructive …