Background: Open Access Guidelines Zalecenia Polskiego Towarzystwa Chorób Płuc
dotyczące rozpoznawania, leczenia i zapobiegania gruźlicy u dorosłych i dzieci

Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here …

We developed a DNA sequencing-based method to detect mutations in the genome of drug-resistant
Mycobacterium tuberculosis. Drug resistance in M. tuberculosis is caused by …

Diagnozowanie gruźlicy oparte na bakteryjnym czynniku etiologicznym ma już ponad 100-letnią
historię. Nowoczesna terapia rozpoczęła się jednak dopiero po II wojnie światowej …

A total of 105 rifampin (RMP)- and/or isoniazid (INH)-resistant strains of Mycobacterium
tuberculosis isolated from different parts of Poland in 2000 were screened for mutations …

Pyrazinamide (PZA) is a prodrug that is converted to pyrazinoic acid by the enzyme pyrazinamidase,
encoded by the pncA gene in Mycobacterium tuberculosis . Molecular identification …

We demonstrated that not whole Mycobacterium tuberculosis but its particular antigens,
hsp70 Mtb , hsp65 Mtb , and hsp16 Mtb , are present in lymph node tissues of patients with …

A total of 31 of thiourea derivatives was prepared reacting 3-(trifluoromethyl)aniline and
commercial aliphatic and aromatic isothiocyanates. The yields varied from 35% to 82%. All …

The investigations of new pyrazine and pyridine derivatives showing an antibacterial activity
have been made. Upon treatment of 3-chloro-2-cyanopyrazine [1] and 2-chloro-3-…

Currently, mutations in three genes, namely rrs, rpsL, and gidB, encoding 16S rRNA, ribosomal
protein S12, and 16S rRNA-specific methyltransferase, respectively, are considered to …