Epithelial tissues protecting organs from the environment are the first-line of defense against
pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain …

Multiple K + channels are expressed in the respiratory epithelium lining airways and alveoli.
Of the three main classes [1) voltage-dependent or Ca 2+ -activated, 6-transmembrane …

Sodium absorption by an amiloride-sensitive channel is the main driving force of lung liquid
clearance at birth and lung edema clearance in adulthood. In this study, we tested whether …

Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic
pathogen Pseudomonas aeruginosa and severe neutrophilic pulmonary inflammation. P. …

The seasonal nature of outbreaks of respiratory viral infections with increased transmission
during low temperatures has been well established. Accordingly, temperature has been …

Efficient repair of epithelial tissue, which is frequently exposed to insults, is necessary to
maintain its functional integrity. It is therefore necessary to better understand the biological and …

Airway damage and remodelling are important components of lung pathology progression
in cystic fibrosis (CF). Although repair mechanisms are engaged to restore the epithelial …

Severe lesions of airway epithelia are observed in cystic fibrosis (CF) patients. The regulatory
mechanisms of cell migration and proliferation processes, involved in the repair of injured …

Airway epithelial cells are key initial innate immune responders in the fight against respiratory
viruses, primarily via the secretion of antiviral and proinflammatory cytokines that act in an …

Cystic fibrosis (CF)-related diabetes (CFRD) has become a critical complication that seriously
affects the clinical outcomes of CF patients. Although CFRD has emerged as the most …