[HTML][HTML] Outcome of patients with non–small cell lung cancer and brain metastases treated with checkpoint inhibitors
…, A Gazzah, C Caramella, J Adam, E Lechapt… - Journal of Thoracic …, 2019 - Elsevier
Introduction Although frequent in NSCLC, patients with brain metastases (BMs) are often
excluded from immune checkpoint inhibitor (ICI) trials. We evaluated BM outcome in a less-…
excluded from immune checkpoint inhibitor (ICI) trials. We evaluated BM outcome in a less-…
Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation
…, A Mackay, S Ghermaoui, E Lechapt… - Acta …, 2020 - Springer
Diffuse midline gliomas (DMG) H3 K27M-mutant was introduced in the 2016 WHO Classification
of Tumors of the Central Nervous System, unifying diffuse intrinsic pontine gliomas (…
of Tumors of the Central Nervous System, unifying diffuse intrinsic pontine gliomas (…
NTRK‐rearranged spindle cell neoplasms are ubiquitous tumours of myofibroblastic lineage with a distinct methylation class
…, F Bourdeaut, L Cardoen, L Hasty, E Lechapt… - …, 2023 - Wiley Online Library
Aims NTRK gene fusions have been described in a wide variety of central nervous system (CNS)
and soft tissue tumours, including the provisional tumour type ‘spindle cell neoplasm, …
and soft tissue tumours, including the provisional tumour type ‘spindle cell neoplasm, …
MRI atlas of IDH wild-type supratentorial glioblastoma: probabilistic maps of phenotype, management, and outcomes
…, F Dhermain, JF Meder, F Chrétien, E Lechapt… - Radiology, 2019 - pubs.rsna.org
Background Tumor location is a main prognostic parameter in patients with glioblastoma.
Probabilistic MRI-based brain atlases specifying the probability of tumor location associated …
Probabilistic MRI-based brain atlases specifying the probability of tumor location associated …
[HTML][HTML] Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA …
…, E Wahler, M Pagčs, F Andreiuolo, E Lechapt… - Acta Neuropathologica …, 2021 - Springer
The cIMPACT-NOW Update 7 has replaced the WHO nosology of “ependymoma, RELA
fusion positive” by “Supratentorial-ependymoma, C11orf95-fusion positive”. This modification …
fusion positive” by “Supratentorial-ependymoma, C11orf95-fusion positive”. This modification …
An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET: CREB‐fused broadening the spectrum of tumor …
…, C Benevello, L Hasty, A Gareton, E Lechapt… - Brain …, 2022 - Wiley Online Library
FET:CREB fusions have been described in a variety of tumors from various phenotypes.
Recently, these fusion transcripts were reported in intracranial tumors, variably named …
Recently, these fusion transcripts were reported in intracranial tumors, variably named …
[HTML][HTML] The EP300:BCOR fusion extends the genetic alteration spectrum defining the new tumoral entity of “CNS tumors with BCOR internal tandem duplication”
…, A de Barros, J Nicolau, A Gareton, E Lechapt… - Acta Neuropathologica …, 2020 - Springer
High-grade neuroepithelial tumors with the BCOR alteration (HGNET-BCOR) were isolated
by a distinct methylation profile from a series of central nervous system (CNS) primitive …
by a distinct methylation profile from a series of central nervous system (CNS) primitive …
[HTML][HTML] Pediatric methylation class HGNET-MN1: unresolved issues with terminology and grading
…, S Caron, F Andreiuolo, A Gareton, E Lechapt… - Acta neuropathologica …, 2019 - Springer
High-grade neuroepithelial tumor with MN1 alteration (HGNET-MN1) is a rare, recently
described central nervous system (CNS) entity with a distinct methylation profile, which was …
described central nervous system (CNS) entity with a distinct methylation profile, which was …
[HTML][HTML] Feasibility, Safety and Impact on Overall Survival of Awake Resection for Newly Diagnosed Supratentorial IDH-Wildtype Glioblastomas in Adults
…, M Baroud, B Trancart, C Oppenheim, E Lechapt… - Cancers, 2021 - mdpi.com
Simple Summary A few studies have suggested the benefits of awake surgery by maximizing
the extent of resection while preserving neurological function and improving survival in high…
the extent of resection while preserving neurological function and improving survival in high…
[HTML][HTML] The histomolecular criteria established for adult anaplastic pilocytic astrocytoma are not applicable to the pediatric population
Pilocytic astrocytoma (PA) is the most common pediatric glioma, arising from a single driver
MAPK pathway alteration. Classified as a grade I tumor according to the 2016 WHO …
MAPK pathway alteration. Classified as a grade I tumor according to the 2016 WHO …