The 3D printing of gelatin methacrylamide cell-laden tissue-engineered constructs with high cell viability

T Billiet, E Gevaert, T De Schryver, M Cornelissen… - Biomaterials, 2014 - Elsevier
In the present study, we report on the combined efforts of material chemistry, engineering and
biology as a systemic approach for the fabrication of high viability 3D printed macroporous …

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

EK Persson, K Verstraete, I Heyndrickx, E Gevaert… - Science, 2019 - science.org
INTRODUCTION Spontaneous protein crystallization rarely occurs in vivo. When it does,
crystals are generated, which sustain long-term protein storage or enable the slow release of …

Chronic rhinosinusitis in Asia

Y Zhang, E Gevaert, H Lou, X Wang, L Zhang… - Journal of Allergy and …, 2017 - Elsevier
Chronic rhinosinusitis (CRS), although possibly overdiagnosed, is associated with a high
burden of disease and is often difficult to treat in those truly affected. Recent research has …

Biologics for chronic rhinosinusitis with nasal polyps

…, N Zhang, C Cavaliere, W Weiping, E Gevaert… - Journal of Allergy and …, 2020 - Elsevier
With the increasing recognition of the role of type 2 immune responses in chronic rhinosinusitis,
its severity, recurrence, and comorbidities, several biologics targeting IL-4, IL-5, and IL-…

Barrier function of the nasal mucosa in health and type‐2 biased airway diseases

N Zhang, K Van Crombruggen, E Gevaert, C Bachert - Allergy, 2016 - Wiley Online Library
The mucosal lining of the upper airways represents the outer surface of the body to the ambient
air and its contents and is prepared for it as the first line of defense. Apart from the well‐…

Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation

E Gevaert, N Zhang, O Krysko, F Lan… - Journal of Allergy and …, 2017 - Elsevier
Background Chronic rhinosinusitis with nasal polyps is characterized by T H 2-biased
eosinophilic inflammation. Eosinophils have been shown to generate so-called extracellular …

A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps

…, N Zhang, H Nauwynck, C Bachert, E Gevaert - Journal of Allergy and …, 2021 - Elsevier
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with
severe type 2 immune reactions in the white population. However, recent findings suggest …

Type 2 inflammation in chronic rhinosinusitis without nasal polyps: another relevant endotype

…, N Zhang, H Nauwynck, C Bachert, E Gevaert - Journal of Allergy and …, 2020 - Elsevier
Background Chronic rhinosinusitis without nasal polyps (CRSsNP) is mainly considered a
type 1 mediated disease. The role and clinical significance of type 2 immune responses in …

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

E Gevaert, T Delemarre, J De Volder… - Journal of Allergy and …, 2020 - jacionline.org
To the Editor: Since their discovery, Charcot-Leyden crystals (CLCs) have been considered
merely a degradation product and marker of eosinophilic inflammation. 1 CLCs are …

Quantitative Contrasts in the Photopolymerization of Acrylamide and Methacrylamide‐F unctionalized Gelatin Hydrogel Building Blocks

T Billiet, BV Gasse, E Gevaert… - Macromolecular …, 2013 - Wiley Online Library
The synthesis and evaluation of gelatin acrylamide as an alternative to the well‐established
gelatin methacrylamide are reported. High‐resolution magic angle spinning NMR is used for …