Importance In adults in whom weaning from invasive mechanical ventilation is difficult,
noninvasive ventilation may facilitate early liberation, but there is uncertainty about its …

Background Lung cancer outcomes in the UK are worse than in many other developed nations.
Symptom awareness campaigns aim to diagnose patients at an earlier stage to improve …

Atelectasis is derived from the Greek words ateles and ektasis, meaning incomplete expansion.
It is also referred to as collapse of the lung. Atelectasis is the loss of lung volume, either …

Air leaks can be defined as any extrusion of air from normal gas-filled cavities including the
upper airway, sinuses, tracheobronchial tree, and gastrointestinal (GI) tract. Clinical …

Introduction Malignant pleural mesothelioma (MPM) is difficult to diagnose. An accurate
blood biomarker could prompt specialist referral or be deployed in future screening. In earlier …

BACKGROUND Invasive mechanical ventilation (IMV) is a life-saving intervention. Following
resolution of the condition that necessitated IMV, a spontaneous breathing trial (SBT) is …

The National Lung Screening Trial (NLST) demonstrated that low-dose computed tomography
(LDCT) screening reduced lung cancer mortality by 20% [1]. Lung cancer screening was …

Pleural effusion is defined as the excessive accumulation of fluid in the pleural space,
indicating an imbalance between pleural fluid formation and removal. The presence of a pleural …

Infectious complications are a significant cause of morbidity and mortality in patients with
haematological disorders. Relative risks and severity vary with underlying disease. …

Introduction Current guidelines recommend either administration of talc slurry via an
intercostal drain or talc poudrage by thoracoscopy for the treatment of symptomatic malignant …