Mutations of the TGF‐β type II receptor BMPR2 in pulmonary arterial hypertension

…, B Patel, EC Schwalbe, E Gruenig… - Human …, 2006 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is clinically characterized by a sustained elevation in
mean pulmonary artery pressure leading to significant morbidity and mortality. The disorder …

Borderline pulmonary arterial pressure is associated with decreased exercise capacity in scleroderma

…, W Salmhofer, W Graninger, E Gruenig… - American journal of …, 2009 - atsjournals.org
Rationale: Pulmonary arterial hypertension is associated with impaired exercise capacity
and decreased survival in patients with scleroderma. Randomized controlled studies showed …

Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension

…, J Ley-Zaporozhan, HU Kauczor, H Klose, E Gruenig - European …, 2013 - Springer
Objectives To evaluate whether careful exercise training improves pulmonary perfusion and
blood flow in patients with pulmonary hypertension (PH), as assessed by magnetic …

Exercise right heart catheterisation before and after pulmonary endarterectomy in patients with chronic thromboembolic disease

…, A Rieth, MJ Richter, E Gruenig… - European …, 2018 - Eur Respiratory Soc
Symptomatic patients with chronic thromboembolic disease (CTED) without pulmonary
hypertension often show an excessive increase in mean pulmonary arterial pressure (MPAP) …

Impairment of respiratory muscle function in pulmonary hypertension

…, H Klose, HA Ghofrani, MM Hoeper, E Gruenig… - Clinical …, 2008 - portlandpress.com
It has been suggested that impaired respiratory muscle function occurs in patients with PH (pulmonary
hypertension); however, comprehensive investigations of respiratory muscle …

Assessment of pulmonary arterial pressure during exercise in collagen vascular disease: echocardiography vs right-sided heart catheterization

…, FC Fuerst, R Thonhofer, P Ofner-Kopeinig, E Gruenig… - Chest, 2010 - Elsevier
Background This study compared the results of exercise Doppler echocardiography (EDE)
with right-sided heart catheterization (RHC) and evaluated the combination of EDE and …

Adult patients with congenital heart disease and pulmonary arterial hypertension: first open prospective multicenter study of bosentan therapy

…, N Gilbert, R Ewert, C Witt, E Gruenig… - American heart …, 2005 - Elsevier
BACKGROUND: Endothelin receptor antagonism has been introduced as an effective oral
therapy of patients with idiopathic pulmonary arterial hypertension. In view of the …

Acute hemodynamic effects of single‐dose sildenafil when added to established bosentan therapy in patients with pulmonary arterial hypertension: results of the …

E Gruenig, E Michelakis, JL Vachiéry… - The Journal of …, 2009 - Wiley Online Library
This study investigated the acute pharmacodynamic effects of sildenafil in patients with
pulmonary arterial hypertension (PAH) and concomitant bosentan treatment, in view of a mutual …

Value of MR phase-contrast flow measurements for functional assessment of pulmonary arterial hypertension

S Ley, D Mereles, M Puderbach, E Gruenig… - European …, 2007 - Springer
Goals of our study were to compare the pulmonary hemodynamics between healthy
volunteers and patients with pulmonary arterial hypertension (PAH) and correlate MR flow …

Echocardiography in pulmonary hypertension

E Bossone, F Ferrara, E Gruenig - Current opinion in cardiology, 2015 - journals.lww.com
Advances in echocardiography and the multimodality imaging approach continue to provide
new understandings and opportunities for the study of the right heart–pulmonary circulation …