User profiles for Eckart Meese

Eckart Meese

Professor für Humangenetik, Saarland University
Verified email at uks.eu
Cited by 23303

Distribution of miRNA expression across human tissues

…, B Meder, C Stähler, E Meese… - Nucleic acids …, 2016 - academic.oup.com
We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in
61 tissue biopsies of different organs from two individuals collected post-mortem. One …

[HTML][HTML] Emerging concepts of miRNA therapeutics: from cells to clinic

C Diener, A Keller, E Meese - Trends in Genetics, 2022 - cell.com
MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …

[HTML][HTML] New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing

…, MRJ Carlson, B Meder, N Blin, E Meese… - Nature …, 2012 - nature.com
The Tyrolean Iceman, a 5,300-year-old Copper age individual, was discovered in 1991 on
the Tisenjoch Pass in the Italian part of the Ötztal Alps. Here we report the complete genome …

[HTML][HTML] Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls

…, M Scheffler, HP Lenhof, K Ruprecht, E Meese - PloS one, 2009 - journals.plos.org
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous
system, which is heterogenous with respect to clinical manifestations and response to …

[HTML][HTML] A blood based 12-miRNA signature of Alzheimer disease patients

…, C Stähler, CJG Lang, B Meder, T Bartfai, E Meese… - Genome biology, 2013 - Springer
Background Alzheimer disease (AD) is the most common form of dementia but the identification
of reliable, early and non-invasive biomarkers remains a major challenge. We present a …

An estimate of the total number of true human miRNAs

…, FA Grässer, HP Lenhof, A Keller, E Meese - Nucleic acids …, 2019 - academic.oup.com
While the number of human miRNA candidates continuously increases, only a few of them
are completely characterized and experimentally validated. Toward determining the total …

[HTML][HTML] Multiply infected spleen cells in HIV patients

…, G Bocharov, V Jung, U Fischer, E Meese… - Nature, 2002 - nature.com
The genome of the human immunodeficiency virus is highly prone to recombination 1 , 2 , 3
, although it is not obvious whether recombinants arise infrequently or whether they are …

Lymphocyte‐specific chemokine receptor CXCR3: regulation, chemokine binding and gene localization

…, P Loetscher, N Brass, E Meese… - European journal of …, 1998 - Wiley Online Library
Expression of CXCR3, the receptor for the CXC chemokines IFN‐γ‐inducible 10‐kDa protein
(IP10) and monokine induced by IFN‐γ (Mig), in human T lymphocytes and their responses …

GeneTrail—advanced gene set enrichment analysis

…, YA Elnakady, R Müller, E Meese… - Nucleic acids …, 2007 - academic.oup.com
We present a comprehensive and efficient gene set analysis tool, called ‘GeneTrail’ that offers
a rich functionality and is easy to use. Our web-based application facilitates the statistical …

Toward the blood-borne miRNome of human diseases

…, B Meder, JD Hoheisel, A Franke, E Meese - Nature …, 2011 - nature.com
In a multicenter study, we determined the expression profiles of 863 microRNAs by array
analysis of 454 blood samples from human individuals with different cancers or noncancer …