Globally, there are now over 160 million confirmed cases of COVID-19 and more than 3
million deaths. While the majority of infected individuals recover, a significant proportion …

The past decade has seen an explosion in research focusing on innate immunity. Through
a wide range of mechanisms including phagocytosis, intracellular killing and activation of …

… In one recent study CXCL8, soluble intracellular adhesion molecule 1 (sICAM-1), and soluble
endothelial selectin (E selectin) (all of which are required for neutrophil migration from the …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated
with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 …

… to opsonize E. coli as efficiently as serum from young donors, unopsonized FITC-labeled E.
… from a single donor to phagocytose the E. coli was determined. Unopsonized (40 μl) FITC …

Frailty is a common negative consequence of ageing. Sarcopenia, the syndrome of loss of
muscle mass, quality and strength, is more common in older adults and has been considered …

Immunosenescence is the functional deterioration of the immune system during natural
aging. Despite increased susceptibility to bacterial infections in older adults, age-associated …

… Elizabeth Sapey1, … This web only file has been produced by the BMJ Publishing Group
from an electronic file supplied by the author(s) and has not been edited for content. …

Neutrophil extracellular traps ( NET s) are a recently discovered addition to the defensive
armamentarium of neutrophils, assisting in the immune response against rapidly dividing …

… vitamin E radical. Ascorbate acts by donating electrons to lipid peroxyls, or to vitamin E
radical, returning them to safe states, whilst itself becoming the very stable ascorbate radical [35]. …