User profiles for E. Barreiro

BARREIRO E

- Verified email at upf.edu - Cited by 25280

Eliezer J. Barreiro

- Verified email at ccsdecania.ufrj.br - Cited by 17841

Molecular hybridization: a useful tool in the design of new drug prototypes

…, V da Silva Bolzani, EJ Barreiro… - Current medicinal …, 2007 - ingentaconnect.com
Molecular hybridization is a new concept in drug design and development based on the
combination of pharmacophoric moieties of different bioactive substances to produce a new …

Bioisosterism: a useful strategy for molecular modification and drug design

LM Lima, EJ Barreiro - Current medicinal chemistry, 2005 - ingentaconnect.com
… Although this isosteric exchange is rare in drugs, the modification of molecular volume by
the substitution C x Si x Ge, producing bioisosteres 45, 46 and 47, results in conformational …

An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease

…, M Decramer, R Casaburi, E Barreiro… - American journal of …, 2014 - atsjournals.org
Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance, …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

…, D Barilā, PG Barlow, SJ Barmada, E Barreiro… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered the …

The methylation effect in medicinal chemistry

EJ Barreiro, AE Kümmerle, CAM Fraga - Chemical reviews, 2011 - ACS Publications
The monovalent methyl group is derived from methane through the removal of a hydrogen
atom, 1 and its etymology is directly related to the discovery of methanol. 2 The first reports of …

[HTML][HTML] Control of confounding and reporting of results in causal inference studies. Guidance for authors from editors of respiratory, sleep, and critical care journals

…, J Bakker, ZK Ballas, PG Bardin, E Barreiro… - Annals of the …, 2019 - atsjournals.org
The views and recommendations made in this document do not represent the official position
of any publisher or professional medical society. This document has not been endorsed by …

Tumor markers (CEA, CA 125, CYFRA 21-1, SCC and NSE) in patients with non-small cell lung cancer as an aid in histological diagnosis and prognosis: comparison …

…, E Canals, N Viņolas, A Marquez, E Barreiro… - Tumor biology, 2003 - karger.com
CEA, CA 125, SCC, CYFRA 21-1 and NSE were prospectively studied in 211 patients with
non-small cell lung cancer and compared with clinical parameters (age, sex, Karnofsky Index, …

From nature to drug discovery: the indole scaffold as a 'privileged structure'

FR de Sa Alves, EJ Barreiro… - Mini reviews in …, 2009 - ingentaconnect.com
The indole scaffold probably represents one of the most important structural subunits for the
discovery of new drug candidates. The demonstration that many alkaloids contain the indole …

β-lactam antibiotics: An overview from a medicinal chemistry perspective

…, BNM da Silva, G Barbosa, EJ Barreiro - European journal of …, 2020 - Elsevier
… Tons of 6-APA (18) are industrially-produced through the PnG (1) and PnV (9) hydrolysis
catalyzed by penicillin acylase (isolated from E. coli) and are used as starting material in the …

ERS statement on respiratory muscle testing at rest and during exercise

…, A Aliverti, T Babb, E Barreiro… - European …, 2019 - Eur Respiratory Soc
Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …