[HTML][HTML] Effectiveness of Intermittent Hypoxia–Hyperoxia Therapy in Different Pathologies with Possible Metabolic Implications

…, MN Popescu, FL Popa, L Pazara, DE Tofolean - Metabolites, 2023 - mdpi.com
Intermittent oxygen therapy (IHT), initially used in the hypoxic administration variant, has
been shown to be effective in various pathologies studied, from cardiopulmonary to vascular …

[HTML][HTML] Biological therapies targeting the type 2 inflammatory pathway in severe asthma

…, AC Ilie, C Oancea, D Tofolean - Experimental and …, 2021 - spandidos-publications.com
Asthma is a variable chronic respiratory disease characterized by airway inflammation and
hyperresponsiveness, bronchoconstriction, and mucus hypersecretion. While most patients …

Lethal disseminated tuberculosis in patients under biological treatment–two clinical cases and a short review

E Dantes, DE Tofolean, AP Fildan… - Journal of …, 2018 - journals.sagepub.com
Tumour necrosis factor (TNF)-α inhibitors are highly used in Romania for the treatment of
autoimmune disorders, such as rheumatoid arthritis (RA), psoriasis, inflammatory bowel …

Aging and extrapulmonary effects of chronic obstructive pulmonary disease

…, M Frandes, E Dantes, DE Tofolean - … interventions in aging, 2017 - Taylor & Francis
Introduction People with COPD have a decline in functional status, but little is known about
the rate of decline and factors that contribute. Of particular concern is the decline in cognitive …

[HTML][HTML] The efficacy of a mobile phone application to improve adherence to treatment and self-management in people with chronic respiratory disease in Romanian …

…, AP Fildan, C Oancea, DE Tofolean - BMC Health Services …, 2020 - Springer
Background Many studies assessed the effect of mobile phone applications on self-management
outcomes in patients with asthma, but all of them presented variable results. In this …

[HTML][HTML] Clinicopathological outlines of post-COVID-19 pulmonary fibrosis compared with idiopathic pulmonary fibrosis

…, M Enciu, GI Băltățescu, AA Nicolau, DE Tofolean… - Biomedicines, 2023 - mdpi.com
This review brings together the current knowledge regarding the risk factors and the clinical,
radiologic, and histological features of both post-COVID-19 pulmonary fibrosis (PCPF) and …

[PDF][PDF] Clinical presentation of a patient with cutis laxa with systemic involvement: a case report

DE Tofolean, L Mazilu, F Stăniceanu, L Mocanu… - Rom J Morphol …, 2015 - rjme.ro
Cutis laxa (CL) or elastolysis is a rare inherited or acquired connective tissue disorder in
which the skin becomes inelastic and hangs loosely in folds (Mitra et al., 2013). The clinical …

[HTML][HTML] Endothelial dysfunction: The possible link between cardiovascular comorbidities and phenomenon of inflammaging from COPD

…, D Traila, M Marc, RM Rajnoveanu, DE Tofolean… - Medicine, 2022 - journals.lww.com
Aging is a risk factor for many chronic noncommunicable diseases, including chronic
obstructive pulmonary disease (COPD), which is often associated with cardiovascular disease (…

Ethical aspects of communication with cancer patients

…, AP Suceveanu, D Tofolean… - Revista Romana de …, 2010 - search.proquest.com
Over the previous several decades numerous changes have occurred in the medical care of
cancer patients. In the midst of diagnostic and therapeutic advances, another significant …

Critical review: what cell types are the lung telocytes?

…, S Hostiuc, AP Fildan, DE Tofolean - The Anatomical …, 2020 - Wiley Online Library
Telocytes (TCs) are stromal cells defined by peculiar long, thin, moniliform prolongations
known as telopodes. When isolated, their morphology often lacks the specificity for the proper …