Lymph node metastasis is a frequent reason for adverse clinical outcome in many epithelial
neoplasms, including head and neck squamous cell carcinoma. The mechanisms …

OBJECTIVE. The purpose of our study was to investigate the potential role of MRI in the
preoperative characterization of the histologic type of testicular tumors and, more specifically, to …

Recent observations suggest an implication of the cyclooxygenase-2 (COX-2) in tumor
lymphangiogenesis through an upregulation of vascular endothelial growth factor-C expression. …

Purpose: Tumor angiogenesis is crucial for both the growth of the primary tumor and the
development of metastases. Among the factors causing tumor angiogenesis, vascular …

Background: Tumor angiogenesis is an absolute requirement for tumor growth and a prognostic
factor for various malignant neoplasms. Recent reports in the literature have addressed …

Background/Purpose Malignant pleural effusion is a frequent situation in pulmonary medicine.
However, it is sometimes difficult to recognize the underlying etiology. The aim of this …

The aim of the present study was to evaluate the association of vascular endothelial growth
factor (VEGF) and its receptor, KDR/Flk-1, with tumor grade, microvessel density (MVD) and …

Purpose Estrogen receptor β (ERβ) is the second identified receptor mediating the effects of
estrogen on target tissues. The role of ERβ in cancer pathobiology is largely unknown, …

Numerous studies indicate the importance of hypoxia-induced pathway in tumor angiogenesis,
but in vivo studies examining the importance of this mechanism in prognosis of patients …

Endoglin (CD105) is a proliferation-associated protein abundantly expressed in angiogenic
endothelial cells. Recent studies revealed that CD105 is intensively expressed in tumor …