The asymmetric allylation and crotylation of aromatic aldehydes with allylic trichlorosilanes
can be promoted by chiral phosphoramides in high yield and modest enantiomeric excess. …

Alpha rules: A thiourea acts as an efficient organocatalyst for the glycosylation of protected
galactals to form oligosaccharides containing a 2-deoxymonosaccharide moiety. The reaction …

O-(Silacyclobutyl) keteneacetals derived from esters, thiol esters, and amidesunderwent
facile aldol addition with a variety of aldehydes at room temperature without the need for …

A practical approach has been developed to convert glucals and rhamnals into disaccharides
or glycoconjugates with high α‐selectivity and yields (77–97 %) using a trans‐fused cyclic …

A series of saligenin β 2 adrenoceptor agonist antedrugs having high clearance were prepared
by reacting a protected saligenin oxazolidinone with protected hydroxyethoxyalkoxyalkyl …

The current interest in solid‐phase organic synthesis has led to a renewed interest in a
complementary technique in which solid supported reagents are used in solution phase chemistry…

The addition of allylic trichlorosilanes to benzaldehyde promoted by chiral phosphoramides
to give the enantioenriched homoallylic alcohol has been investigated. In a survey of Lewis …

Both chiral and achiral phosphoramides of diverse structure were prepared from diamines
by the coupling to phosphorus(V) or phosphorus(III) reagents. Several enantiopure 1,2-…

The use of a bifunctional cinchona/thiourea organocatalyst for the direct and α-stereoselective
glycosylation of 2-nitrogalactals is demonstrated for the first time. The conditions are mild, …

PROTACs have recently emerged as a novel paradigm in drug discovery. They can hijack
existing biological machinery to selectively degrade proteins of interest, in a catalytic fashion. …