User profiles for Deirdre Fitzgerald-Hughes
Deirdre Fitzgerald HughesRoyal College of Surgeons in Ireland Verified email at rcsi.com Cited by 1521 |
[HTML][HTML] Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
…, M Tavakol, CH Hearnden, D Fitzgerald-Hughes… - PLoS …, 2015 - journals.plos.org
Mechanisms of protective immunity to Staphylococcus aureus infection in humans remain
elusive. While the importance of cellular immunity has been shown in mice, T cell responses in …
elusive. While the importance of cellular immunity has been shown in mice, T cell responses in …
[HTML][HTML] Effect of essential oils of Syzygium aromaticum and Cinnamomum zeylanicum and their major components on biofilm production in Staphylococcus aureus …
Bovine mastitis is an inflammation of the mammary glands of cows and causes significant
economic losses in dairy cattle. Staphylococcus aureus is one of the microorganisms most …
economic losses in dairy cattle. Staphylococcus aureus is one of the microorganisms most …
Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides
…, JP O'Gara, D Fitzgerald-Hughes… - The Journal of …, 2017 - academic.oup.com
Here, we demonstrate that antimicrobial peptides (AMPs) are an effective antibiofilm treatment
when applied as catheter lock solutions (CLSs) against S. aureus biofilm infections. The …
when applied as catheter lock solutions (CLSs) against S. aureus biofilm infections. The …
[HTML][HTML] Improving the management and treatment of diabetic foot infection: challenges and research opportunities
Diabetic foot infection (DFI) management requires complex multidisciplinary care pathways
with off-loading, debridement and targeted antibiotic treatment central to positive clinical …
with off-loading, debridement and targeted antibiotic treatment central to positive clinical …
Air and surface contamination patterns of meticillin-resistant Staphylococcus aureus on eight acute hospital wards
…, N Walley, S McHugh, D Fitzgerald-Hughes… - Journal of Hospital …, 2014 - Elsevier
Background Meticillin-resistant Staphylococcus aureus (MRSA) can be recovered from
hospital air and from environmental surfaces. This poses a potential risk of transmission to …
hospital air and from environmental surfaces. This poses a potential risk of transmission to …
Resistance to third-generation cephalosporins in human non-typhoidal Salmonella enterica isolates from England and Wales, 2010–12
…, E De Pinna, D Fitzgerald-Hughes… - Journal of …, 2014 - academic.oup.com
Objectives To identify the mechanism(s) underlying cefotaxime resistance in 118 of 21 641 (0.55%)
non-typhoidal Salmonella enterica isolates collected from humans throughout …
non-typhoidal Salmonella enterica isolates collected from humans throughout …
[HTML][HTML] A novel dual-functioning ruthenium (II)–arene complex of an anti-microbial ciprofloxacin derivative—Anti-proliferative and anti-microbial activity
Z Ude, I Romero-Canelón, B Twamley… - Journal of inorganic …, 2016 - Elsevier
7-(4-(Decanoyl)piperazin-1-yl)-ciprofloxacin, CipA, (1) which is an analogue of the antibiotic
ciprofloxacin, and its ruthenium(II) complex [Ru(η 6 -p-cymene)(CipA -H )Cl], (2) have been …
ciprofloxacin, and its ruthenium(II) complex [Ru(η 6 -p-cymene)(CipA -H )Cl], (2) have been …
When are the hands of healthcare workers positive for meticillin-resistant Staphylococcus aureus?
…, A Dolan, O Sherlock, D Fitzgerald-Hughes… - Journal of Hospital …, 2010 - Elsevier
Hand hygiene is a key component in reducing infection. There are few reports on the
prevalance of meticillin-resistant Staphlococcus aureus (MRSA) on healthcare workers' (HCWs') …
prevalance of meticillin-resistant Staphlococcus aureus (MRSA) on healthcare workers' (HCWs') …
Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: two novel alternatives
D Fitzgerald-Hughes, M Devocelle… - FEMS Immunology & …, 2012 - academic.oup.com
The majority of antibiotics currently used to treat methicillin-resistant Staphylococus aureus (MRSA)
infections target bacterial cell wall synthesis or protein synthesis. Only daptomycin …
infections target bacterial cell wall synthesis or protein synthesis. Only daptomycin …
[HTML][HTML] Cytokine responses to Staphylococcus aureusbloodstream infection differ between patient cohorts that have different clinical courses of infection
Background The clinical course of Staphylococcus aureus bloodstream infection is unpredictable
and bacterial virulence, host immune response and patient characteristics are among …
and bacterial virulence, host immune response and patient characteristics are among …