An essential but insufficient step for apical sorting of glycosylphosphatidylinositol (GPI)-anchored
proteins (GPI-APs) in epithelial cells is their association with detergent-resistant …

Prions are defined as infectious agents that comprise only proteins and are responsible for
transmissible spongiform encephalopathies (TSEs) – fatal neurodegenerative diseases that …

… flavescens features: Chiara Pagliuca, Roberta Colicchio, and Paola Salvatore; conceived
and performed confocal microscopy assays: Daniela Sarnataro; conceived the experiments to …

The pathological conversion of cellular prion protein (PrP C ) into the scrapie prion protein (PrP
Sc ) isoform appears to have a central role in the pathogenesis of transmissible …

Adiponectin (Acrp30) exerts protective functions on metabolic and cellular processes as
energy metabolism, cell proliferation and differentiation by two widely expressed receptors, …

The endocannabinoid system has been shown to modulate key cell-signaling pathways
involved in cancer cell growth. In this study, we show that cannabinoid receptor type 1 (CB1) …

ER–TGN contact sites (ERTGoCS) have been visualized by electron microscopy, but their
location in the crowded perinuclear area has hampered their analysis via optical microscopy …

Tumor necrosis factor receptor-associated protein-1 (TRAP1) is a mitochondrial (MITO)
antiapoptotic heat-shock protein. The information available on the TRAP1 pathway describes just …

In immunoglobulin (Ig) light‐chain (LC) (AL) amyloidosis, AL deposition translates into life‐threatening
cardiomyopathy. Clinical and experimental evidence indicates that soluble …

Misfolded and abnormal β-sheets forms of wild-type proteins, such as cellular prion protein (PrP
C ) and amyloid beta (Aβ), are believed to be the vectors of neurodegenerative diseases…