High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus

…, B de Courten, JM Forbes, FY Yap, DM Kaye… - Circulation, 2009 - Am Heart Assoc
Background— Low plasma high-density lipoprotein (HDL) is associated with elevated
cardiovascular risk and aspects of the metabolic syndrome. We hypothesized that HDL modulates …

Effect of sunlight and season on serotonin turnover in the brain

GW Lambert, C Reid, DM Kaye, GL Jennings, MD Esler - The Lancet, 2002 - thelancet.com
… GW Lambert, DM Kaye, and MD Esler were the principal investigators responsible for patient
recruitment, … DM Kaye and GL Jennings did internal jugular catheterisation and blood flow …

Evaluation of Diffuse Myocardial Fibrosis in Heart Failure With Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping

…, J Cherayath, P Aksit, SN Gupta, DM Kaye… - Journal of the American …, 2008 - jacc.org
Objectives : The purpose of this study was to investigate a noninvasive method for quantifying
diffuse myocardial fibrosis with cardiac magnetic resonance imaging (CMRI). Background …

High-fiber diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice

…, NW Rajapakse, A El-Osta, CR Mackay, DM Kaye - Circulation, 2017 - Am Heart Assoc
Background: Dietary intake of fruit and vegetables is associated with lower incidence of
hypertension, but the mechanisms involved have not been elucidated. Here, we evaluated the …

[HTML][HTML] Adverse consequences of high sympathetic nervous activity in the failing human heart

DM Kaye, J Lefkovits, GL Jennings, P Bergin… - Journal of the American …, 1995 - Elsevier
OBJECTIVES.: In view of previous experimental evidence relating sympathetic nervous
overactivity in the heart to myocardial necrosis and ventricular arrhythmias, we prospectively …

Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation

MP Schlaich, E Lambert, DM Kaye, Z Krozowski… - …, 2004 - Am Heart Assoc
There is growing evidence that essential hypertension is commonly neurogenic and is initiated
and sustained by sympathetic nervous system overactivity. Potential mechanisms include …

Controlled trial of continuous positive airway pressure in obstructive sleep apnea and heart failure

DR Mansfield, NC Gollogly, DM Kaye… - American journal of …, 2004 - atsjournals.org
Obstructive sleep apnea (OSA) is highly prevalent among patients with congestive heart
failure (CHF) and may contribute to progression of cardiac dysfunction via hypoxia, elevated …

Air versus oxygen in ST-segment–elevation myocardial infarction

…, B Barger, AH Ellims, AJ Taylor, IT Meredith, DM Kaye - Circulation, 2015 - Am Heart Assoc
Background— Oxygen is commonly administered to patients with ST-elevation–myocardial
infarction despite previous studies suggesting a possible increase in myocardial injury as a …

Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy

MP Schlaich, DM Kaye, E Lambert, M Sommerville… - Circulation, 2003 - Am Heart Assoc
Background— Left ventricular (LV) hypertrophy is an independent risk factor for cardiovascular
morbidity and mortality in hypertensive subjects. Sympathetic activation has been …

Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial)

…, J Shaw, SJ Duffy, A Burrell, P Cameron, DM Kaye - Resuscitation, 2015 - Elsevier
Introduction Many patients who suffer cardiac arrest do not respond to standard
cardiopulmonary resuscitation. There is growing interest in utilizing veno-arterial extracorporeal …