User profiles for D. C. M. Liewald
David CM LiewaldSystems Analyst LBC / CCACE Edinburgh University Verified email at ed.ac.uk Cited by 49170 |
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
…, LJ Launer, B Lehne, T Lehtimäki, DCM Liewald… - Nature …, 2018 - nature.com
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …
We report the largest genetic association study of blood pressure traits (systolic, diastolic …
Common genetic variants influence human subcortical brain structures
…, AJ Heister, D Hoehn, D Kasperaviciute, DCM Liewald… - Nature, 2015 - nature.com
The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …
Sex differences in the adult human brain: evidence from 5216 UK biobank participants
…, S Hunter, E Neilson, DCM Liewald… - Cerebral …, 2018 - academic.oup.com
Sex differences in the human brain are of interest for many reasons: for example, there are
sex differences in the observed prevalence of psychiatric disorders and in some …
sex differences in the observed prevalence of psychiatric disorders and in some …
[HTML][HTML] Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …
with many important life outcomes. We combine cognitive and genetic data from the …
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
…, M Larson, LJ Launer, B Lehne, DCM Liewald… - Nature …, 2017 - nature.com
Elevated blood pressure is the leading heritable risk factor for cardiovascular disease
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …
[HTML][HTML] Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N= 112 151) and 24 GWAS consortia
Causes of the well-documented association between low levels of cognitive functioning and
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
…, NR Lee, J Lee, J Liao, W Lieb, DCM Liewald… - Nature …, 2015 - nature.com
We carried out a trans-ancestry genome-wide association and replication study of blood
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
…, J Luan, RA Scott, SE Harris, DCM Liewald… - Nature …, 2016 - nature.com
High blood pressure is a major risk factor for cardiovascular disease and premature death.
However, there is limited knowledge on specific causal genes and pathways. To better …
However, there is limited knowledge on specific causal genes and pathways. To better …
[HTML][HTML] Novel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …
[HTML][HTML] Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci
Neuroticism is a personality trait of fundamental importance for psychological well-being and
public health. It is strongly associated with major depressive disorder (MDD) and several …
public health. It is strongly associated with major depressive disorder (MDD) and several …