… Author links open overlay panel Dirk Pappert MD a , Rolf Rossaint MD a , Klaus Slama MD
a , Thilo Grüning MD a , … Gattinoni L, Pelosi P, Vitale G, Pesenti A, D’Andrea L, Mascheroni D …

Inhalation of nitric oxide (NO), an endoge‐neous vasodilator, was recently described to
reduce pulmonary vascular resistance, and to improve arterial oxygenation by selective …

… , Dirk Pappert MD a , Klaus Lewandowski MD a , Wolfgang Steudel MD a , Konrad Falke MD
a … Mortality outcome: survived (S), which was hospital discharge, or died (D). Mean ± SE or …

Inhaled nitric oxide (NO) improves systemic oxygenation (Pa O2 /FI O2 ) in adult patients
with acute respiratory distress syndrome (ARDS). However, individual response varies, and …

An exaggerated hypoxic pulmonary vasoconstriction is essential for development of high-altitude
pulmonary edema (HAPE). We hypothesized that susceptibility to HAPE may be …

Exogenous nitric oxide (NO) reduces pulmonary vascular resistance after low-dose inhalation
in patients. To estimate endogenous NO synthesis in the upper respiratory tract, we …

Objective To evaluate the lowest dose of inhaled nitric oxide (NO) in patients with adult
respiratory distress syndrome (ARDS), which is able to improve arterial oxygenation more than 30…

The aim of the present study was to investigate the feasibility and efficacy of bronchoscopic
surfactant administration in a noncontrolled multicentre study in five university centres. A total …

In an attempt to restore functional surfactant to the lungs of patients with the adult respiratory
distress syndrome (ARDS), we have treated six patients within the first 2 days of the onset of …

Objective To compare the effects of inhaled nitric oxide (NO) and an infusion of prostacyclin (PGI
2 ) on right ventricular function in patients with severe acute respiratory distress …