Latent tuberculosis infection (LTBI) is characterised by the presence of immune responses
to previously acquired Mycobacterium tuberculosis infection without clinical evidence of …

In clinical practice, latent infection with M ycobacterium tuberculosis is defined by the presence
of an M . tuberculosis‐specific immune response in the absence of active tuberculosis. …

Introduction Heavy alcohol consumption increases the risk of active tuberculosis (TB).
However, the relation between lower levels of alcohol intake and TB risk remains unclear. We …

Background and aims Isoniazid (INH) is part of the first-line-therapy for tuberculosis (TB) but
can cause drug-induced liver injury (DILI). Several candidate single nucleotide …

Background: Diabetes mellitus (DM) confers a higher risk for tuberculosis (TB). Yet, TB
screening and chemoprophylaxis for latent TB infection (LTBI) in DM remains controversial. We …

Objectives This first cross-sectional survey on latent tuberculosis infection (LTBI) in Singapore
was performed by utilizing the QuantiFERON Gold In-tube (QFT-GIT) assay to collect data …

Background Singapore is an intermediate tuberculosis (TB) incidence country, with a recent
rise in TB incidence from 2008, after a fall in incidence since 1998. This study identified …

Host cell chromatin changes are thought to play an important role in the pathogenesis of
infectious diseases. Here we describe a histone acetylome-wide association study (HAWAS) of …

The tuberculin skin test (TST) and interferon gamma (IFN-γ) release assays (IGRAs) are
used as adjunctive tests for the evaluation of suspected cases of active tuberculosis (TB). …

Experimental studies showed that tea polyphenols may inhibit growth of Mycobacterium
tuberculosis. However, no prospective epidemiologic study has investigated tea drinking and …