Objective— We examined whether plasma levels of angiogenic factors are altered in
plasma of patients with peripheral arterial disease (PAD) and whether these factors affect …

Egfl7 (VE-statin) is a secreted protein mostly specific to the endothelial lineage during
development and in the adult and which expression is enhanced during angiogenesis. Egfl7 …

Objective—To determine the role of Wnt antagonist Dickkopf (DKK) 1 in human endothelial
colony-forming cells (ECFCs) in view of the emerging importance of Wnt pathways in …

Background Fibrogenesis during idiopathic pulmonary fibrosis (IPF) is strongly associated
with abnormal vascular remodeling. Respective abundance of circulating endothelial cells (…

Upregulation of hypoxia-inducible transcription factor-1α (HIF-1α), through prolyl-hydroxylase
domain protein (PHD) inhibition, can be thought of as a master switch that coordinates the …

Background Pulmonary vasodilators in general and prostacyclin therapy in particular, have
markedly improved the outcome of patients with pulmonary arterial hypertension (PAH). As …

Dabigatran etexilate, rivaroxaban and apixaban (DOACs) are widely used and measurement
of their concentration is desirable in certain clinical situations. Target-specific assays are …

The proinflammatory chemokine interleukin 8 exerts potent angiogenic effects on endothelial
cells by interacting with its receptors CXCR1 and CXCR2. As thrombin is also a potent …

Background Endothelial colony forming cells (ECFC) represent a subpopulation of
endothelial progenitor cells involved in endothelial repair. The activation of procoagulant …

… Clément d'Audigier was supported by a research grant from Fondation pour la Recherche
Médicale. We received research grants from Fondation pour la Recherche Médicale (grant …