Fibroblast activation protein–specific PET/CT imaging in fibrotic interstitial lung diseases and lung cancer: a translational exploratory study

M Röhrich, D Leitz, FM Glatting, AK Wefers… - Journal of nuclear …, 2022 - Soc Nuclear Med
Interstitial lung diseases (ILDs) comprise over 200 parenchymal lung disorders. Among
them, fibrosing ILDs, especially idiopathic pulmonary fibrosis, are associated with a poor …

Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: analysis of the first 3,000 Heidelberg cases

AL Volckmar, J Leichsenring, M Kirchner… - … Journal of Cancer, 2019 - Wiley Online Library
Tyrosine kinase inhibitors currently confer the greatest survival gain for nonsmall cell lung
cancer (NSCLC) patients with actionable genetic alterations. Simultaneously, the increasing …

Transbronchial cryobiopsy increases diagnostic confidence in interstitial lung disease: a prospective multicentre trial

J Hetzel, AU Wells, U Costabel… - European …, 2020 - Eur Respiratory Soc
Introduction The accurate diagnosis of individual interstitial lung diseases (ILD) is often
challenging, but is a critical determinant of appropriate management. If a diagnosis cannot be …

Revision and update of the consensus definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer and the Mycoses …

…, B Fisher, T Harrison, CP Heussel… - Clinical Infectious …, 2020 - academic.oup.com
Background Invasive fungal diseases (IFDs) remain important causes of morbidity and
mortality. The consensus definitions of the Infectious Diseases Group of the European …

Automated detection and quantification of brain metastases on clinical MRI data using artificial neural networks

I Pflüger, T Wald, F Isensee, M Schell… - Neuro-oncology …, 2022 - academic.oup.com
Background Reliable detection and precise volumetric quantification of brain metastases (BM)
on MRI are essential for guiding treatment decisions. Here we evaluate the potential of …

Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the …

…, L Drgona, AH Groll, J Guinea, CP Heussel… - The Lancet infectious …, 2019 - thelancet.com
Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality.
Diagnosis is often delayed, and disease tends to progress rapidly. Urgent surgical and medical …

[HTML][HTML] Comparison of MRI and VQ-SPECT as a screening test for patients with suspected CTEPH: CHANGE-MRI study design and rationale

F Lasch, A Karch, A Koch, T Derlin… - Frontiers in …, 2020 - frontiersin.org
The diagnostic strategy for chronic thromboembolic pulmonary hypertension (CTEPH) is
composed of two components required for a diagnosis of CTEPH: the presence of chronic …

Liposomal amphotericin b as initial therapy for invasive mold infection: a randomized trial comparing a high–loading dose regimen with standard dosing (AmBiLoad …

…, AJ Ullmann, E Bouza, CP Heussel… - Clinical infectious …, 2007 - academic.oup.com
Background .Treatment of invasive mold infection in immunocompromised patients remains
challenging. Voriconazole has been shown to have efficacy and survival benefits over …

Pneumonia in febrile neutropenic patients and in bone marrow and blood stem-cell transplant recipients: use of high-resolution computed tomography

CP Heussel, HU Kauczor, GE Heussel… - Journal of Clinical …, 1999 - ascopubs.org
PURPOSE: To obtain statistical data on the use of high-resolution computed tomography (HRCT)
for early detection of pneumonia in febrile neutropenic patients with unknown focus of …

[HTML][HTML] Impact of comorbidities on mortality in patients with idiopathic pulmonary fibrosis

…, J Bruhwyler, U Oltmanns, T Muley, CP Heussel… - PloS one, 2016 - journals.plos.org
Introduction Comorbidities significantly influence the clinical course of idiopathic pulmonary
fibrosis (IPF). However, their prognostic impact is not fully understood. We therefore aimed to …