Lung deposition of BDP/formoterol HFA pMDI in healthy volunteers, asthmatic, and COPD patients

…, G Poli, D Acerbi, R Monno, C Herpich… - Journal of aerosol …, 2010 - liebertpub.com
Background: When inhaling medication, it is essential that drug particles are delivered to all
sites of lung inflammation, including the peripheral airways. The aim of this study was to …

Lung Deposition of the Dry Powder Fixed Combination Beclometasone Dipropionate Plus Formoterol Fumarate Using NEXThaler® Device in Healthy Subjects …

JC Virchow, G Poli, C Herpich, C Kietzig… - Journal of aerosol …, 2018 - liebertpub.com
Background: This study evaluated the lung deposition and the distribution pattern in the
airways of a fixed combination of beclometasone dipropionate (BDP) and formoterol fumarate (…

[HTML][HTML] Higher bioavailability of magnesium citrate as compared to magnesium oxide shown by evaluation of urinary excretion and serum levels after single-dose …

D Kappeler, I Heimbeck, C Herpich, N Naue, J Höfler… - BMC Nutrition, 2017 - Springer
Background The development of several disorders, such as cardiovascular diseases, diabetes
and osteoporosis, has been linked to suboptimal dietary magnesium (Mg) intake. In this …

Lung Deposition of Formoterol HFA (Atimos®/Forair®) in Healthy Volunteers, Asthmatic and COPD Patients

…, D Acerbi, P Brand, C Herpich… - Journal of aerosol …, 2007 - liebertpub.com
In this study, the influence of lung function on lung deposition of a radioactively labeled
Formotoerol HFA MDI (Forair ® ) was investigated. Eighteen subjects were measured: 6 healthy …

[HTML][HTML] Effects of formoterol and tiotropium bromide on mucus clearance in patients with COPD

T Meyer, P Reitmeir, P Brand, C Herpich… - Respiratory …, 2011 - Elsevier
BACKGROUND: Lung mucociliary clearance is impaired in patients with chronic obstructive
pulmonary disease (COPD). Treatment guidelines recommend that patients with COPD …

Lung deposition of the extra fine dry powder fixed combination beclomethasone dipropionate plus formoterol fumarate via the NEXT DPI® in healthy subjects …

F Mariotti, F Sergio, D Acerbi, T Meyer, C Herpich - 2011 - Eur Respiratory Soc
Background: Chiesi has developed the new pocket size, medium air flow resistant, breath
actuated multidose-reservoir dry powder inhaler NEXT DPI®. Objectives: The lung deposition …

Effects of a helium/oxygen mixture on individuals' lung function and metabolic cost during submaximal exercise for participants with obstructive lung diseases

…, A Schulze, IM Katz, AR Martin, C Herpich… - … Journal of Chronic …, 2015 - Taylor & Francis
Background Helium/oxygen therapies have been studied as a means to reduce the
symptoms of obstructive lung diseases with inconclusive results in clinical trials. To better …

Lung Deposition of Alpha1-Proteinase Inhibitor (Human) (A1-PI[H]) Inhalation Solution Using Two Inhalation Modes of the I-neb Adaptive Aerosol Delivery (AAD) …

…, J Edelman, D Kappeler, C Herpich… - Journal of Aerosol …, 2016 - liebertpub.com
Background: In cystic fibrosis (CF) patients, inhalation of alpha 1 -proteinase inhibitor (A 1 -PI)
can prevent or slow down persistent infections and reduce the massive ongoing …

Effect Of Helium/Oxygen Mixtures On The Metabolic Cost Of Exercise For Patients With Obstructive Lung Disease

…, A Schulze, IM Katz, AR Martin, C Herpich… - C35. INSIGHTS INTO …, 2011 - atsjournals.org
2 2 2 other groups both at rest and during exercise, though these results were not
statistically significant. For the 65/35 mixture, due to the high oxygen content, SO increased …

Fasting concentrations and postprandial response of 1, 2-dicarbonyl compounds 3-deoxyglucosone, glyoxal, and methylglyoxal are not increased in healthy older …

C Herpich, B Kochlik, D Weber, C Ott… - The Journals of …, 2022 - academic.oup.com
Dicarbonyl stress describes the increased formation of 1,2-dicarbonyl compounds and is
associated with age-related pathologies. The role of dicarbonyl stress in healthy aging is poorly …