Allergy diagnosis based on purified allergen molecules provides detailed information
regarding the individual sensitization profile of allergic patients, allows monitoring of the …

Background The evolution of the IgE response to the numerous allergen molecules of
Dermatophagoides pteronyssinus is still unknown. Objectives We sought to characterize the …

Asthma, rhinitis, and eczema are complex diseases with multiple genetic and environmental
factors interlinked through IgE-associated and non–IgE-associated mechanisms. …

Background Sensitization to individual cat and dog allergen molecules can contribute
differently to development of allergy to these animals. Objective We sought to investigate the …

Background Component-resolved diagnosis might improve the prediction of future allergy in
young children. Objective We sought to investigate the association between IgE reactivity to …

Background House dust mites (HDMs) represent one of the most important inducers of
respiratory allergies worldwide. Objective We sought to investigate the IgE and IgG reactivity …

Immunoglobulin E (IgE)-associated allergy is the most common immune disorder. More
than 30% of the population suffer from symptoms of allergy which are often severe, disabling, …

We report the three-dimensional structure of the complex between the major respiratory
grass pollen allergen Phl p 2 and its specific human IgE-derived Fab. The Phl p 2-specific …

Background Understanding differences in sensitization profiles at the molecular allergen
level is important for diagnosis, personalized treatment and prevention strategies in allergy. …

Background Atopic dermatitis (AD) is a complex chronic inflammatory disease where
allergens can act as specific triggering factors. Aim To characterize the specificities of IgE-reactivity …