ESC Guidelines 3039 administrative staff and by the referees and supervisory committees
of the two organizations. It is our hope that this huge effort has generated guidelines that will …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

It has been suggested that the metabolic side effects of antihypertensive drugs are responsible
for their failure to reduce cardiovascular morbidity in patients with hypertension. Therefore…

The relationship between abnormalities in carbohydrate metabolism and hypertension was
studied in 143 newly detected hypertensive patients (59% obese) of both sexes (90 males, …

Background Intraportal transplantation of pancreatic islets offers improved glycaemic control
and insulin independence in type 1 diabetes mellitus, but intraportal thrombosis remains a …

Background: Chronic infection with hepatitis B virus, alcohol consumption, and cirrhosis of
the liver are recognized risk factors for primary liver cancer. A few, but not all, studies have …

Cancer incidence was ascertained in a population-based cohort of 51,008 patients in
Uppsala, Sweden, who were given a discharge diagnosis of diabetes mellitus during 1965–83. …

An intrinsic angiotensin system has been described in the pancreas, with angiotensin II
specific receptors being present on both exocrine, endocrine and vascular cells. The aim of the …