Background In allergic asthma, IgE increases airway remodelling but the mechanism is
incompletely understood. Airway remodelling consists of two independent events increased cell …

Asthma is characterized by chronic inflammation and tissue remodeling of the airways.
Remodeling is resistant to pharmaceutical therapies. This study investigated the effect of zinc …

Glycosaminoglycans (GAGs), especially hyaluronic acid (HA), regulate tissue flexibility, cell
motility, and inflammation. Airway smooth muscle cells (ASMCs) of patients with asthma …

Background The rich biodiversity of medicinal plants and their importance as sources of
novel therapeutics and lead compounds warrant further research. Despite advances in …

Background: Increased deposition pro-inflammatory collagen I and III has been shown in
the sub-epithelial airways in asthma. Formoterol has been reported to reduce collagen …

Background: Airway remodelling in asthma is partly due to increased airway smooth muscle
(ASM) mass. We and others reported earlier that steroids alone do not significantly reduce …

Background: Increased extracellular matrix deposition, and more important its pro-inflammatory
composition is a hallmark of airway remodelling in allergic asthma. Objective: a) To …

Underrepresentation of Asian genomes has hindered population and medical genetics
research on Asians, leading to population disparities in precision medicine. By whole-genome …

Palm pressed fibre (PPF) is a lignocellulose biomass generated from palm oil mill that is
rich in cellulose. The present work aimed to combine acid hydrolysis followed by high-pressure …

… team looks forward to potential collaborations and investigators interested in exploring the
possibility of collaborations should contact lead principal investigator Professor Chong Yap …