IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation

…, N van Rooijen, M Shepherd, C McSharry… - The Journal of …, 2009 - journals.aai.org
Alternatively activated macrophages (AAM) play a crucial role in type 2 immunity. Mice
deficient in ST2, a receptor for the latest member of the IL-1 family, IL-33, have impaired type 2 …

CD4+ CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice

…, M Komai-Koma, C Campbell, C McSharry… - The Journal of …, 2003 - journals.aai.org
Regulatory T cells play a major role in modulating the immune response. However, most
information on these cells centers on autoimmunity, and there is also considerable controversy …

Heterogeneous proliferative characteristics of human adult lung fibroblast lines and clonally derived fibroblasts from control and fibrotic tissue

M Jordana, J Schulman, C McSharry, LB Irving… - Am Rev Respir …, 1988 - atsjournals.org
Pulmonary fibrosis results from an altered deposition of collagen within the lung
parenchyma. This alteration is likely the result of both increased fibroblast proliferation and …

T-Cell Responses during Trypanosoma brucei Infections in Mice Deficient in Inducible Nitric Oxide Synthase

AE Millar, J Sternberg, C McSharry, XQ Wei… - Infection and …, 1999 - Am Soc Microbiol
We have investigated the possibility that nitric oxide (NO) synthesis may affect the course of
a trypanosome infection via T-cell responses using mice deficient in inducible NO synthase (…

A role for ST2/IL-33 signalling in fibroblast proliferation utilising a novel transgenic mouse model of pulmonary hypertension

C Church, A Mahmood, C McSharry, D Xu, A Peacock… - 2011 - Eur Respiratory Soc
In this study, we determined if the ST2 receptor and its ligand, interleukin-33 (IL-33) was
involved in mouse PAF proliferation and if ST2-/- mice displayed a pulmonary hypertensive …

[BOOK][B] Endothelin-1 and the use of induced sputum to investigate its role in airway diseases

GW Chalmers - 1999 - search.proquest.com
… of Dr Charlie McSharry. They have been involved in the design and execution of the studies,
and in the preparation of manuscripts and presentation of work. I am grateful to both for their …

[PDF][PDF] CD4+ CD25+ Regulatory T Cells Suppress

CMS Campbell, J Alexander, Y Foo, D Xu, H Liu… - J …, 2003 - researchgate.net
Regulatory T cells play a major role in modulating the immune response. However, most
information on these cells centers on autoimmunity, and there is also considerable controversy …

Effects of hematodinium infection on the Norway lobster, nephrops norvegicus (L.)

GD Stentiford - 2000 - theses.gla.ac.uk
The Norway lobster (Nephrops norvegicus) is one of the most valuable shellfish resources
in the north east Atlantic ocean and considerable knowledge exists with regard to its biology …

[BOOK][B] Role of interleukin-15 and nitric oxide expression in chronic inflammatory disease

BP Leung - 1998 - search.proquest.com
Charlie McSharry for theh guidance and advice. I am grateful also to Prof. Roger
StuiTock for his support and for allowing me to undertake part of this work in his laboratory. …

[PDF][PDF] Harassment Prevalent Problem: Cause of Pain, Rage, Hate

NE McSharry - 1980 - scarab.bates.edu
McSharry Have you ever been called a Jap because you’re from New Jersey and you wear
Kleins? Have you ever been told by a friend to “stop messing with those white women” and …