Background Although heart rate variability (HRV) is altered in a variety of pathological
conditions, the association of reduced HRV with risk for new cardiac events has not been studied …

Although the entire coronary tree is exposed to the atherogenic effect of the systemic risk
factors, atherosclerotic lesions form at specific arterial regions, where low and oscillatory …

BACKGROUND The prognostic implications of alterations in heart rate variability have not
been studied in a large community-based population. METHODS AND RESULTS The first 2 …

Background— Atherosclerotic plaques progress in a highly individual manner. The purposes
of the Prediction of Progression of Coronary Artery Disease and Clinical Outcome Using …

Background— Low endothelial shear stress (ESS) promotes the development of
atherosclerosis; however, its role in the progression of atherosclerotic plaques and evolution to …

Background— Native atherosclerosis and in-stent restenosis are focal and evolve
independently. The endothelium controls local arterial responses by transduction of shear stress. …

Obstruction of critical blood vessels due to thrombosis or embolism is a leading cause of
death worldwide. Here, we describe a biomimetic strategy that uses high shear stress caused …

Objectives. This study sought to examine clinical determinants of heart rate variability and to
report normative reference values for eight heart rate variability measures. Background. …

We performed a prospective, international, observational study of 844 hospitalized patients
with blood cultures positive for Streptococcus pneumoniae. Fifteen percent of isolates had in …

Retrospective studies have suggested that combination antibiotic therapy for severe
bacteremic pneumococcal pneumonia may reduce mortality. We assessed this issue in a …