[PDF][PDF] Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
Cancer-associated IDH mutations are characterized by neomorphic enzyme activity and
resultant 2-hydroxyglutarate (2HG) production. Mutational and epigenetic profiling of a large …
resultant 2-hydroxyglutarate (2HG) production. Mutational and epigenetic profiling of a large …
Quantum computational advantage using photons
Quantum computers promise to perform certain tasks that are believed to be intractable to
classical computers. Boson sampling is such a task and is considered a strong candidate to …
classical computers. Boson sampling is such a task and is considered a strong candidate to …
[HTML][HTML] Experimental entanglement of six photons in graph states
Graph states 1 , 2 , 3 —multipartite entangled states that can be represented by mathematical
graphs—are important resources for quantum computation 4 , quantum error correction 3 , …
graphs—are important resources for quantum computation 4 , quantum error correction 3 , …
Strong quantum computational advantage using a superconducting quantum processor
Scaling up to a large number of qubits with high-precision control is essential in the
demonstrations of quantum computational advantage to exponentially outpace the classical …
demonstrations of quantum computational advantage to exponentially outpace the classical …
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Recurrent mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 have been identified in
gliomas, acute myeloid leukaemias (AML) and chondrosarcomas, and share a novel …
gliomas, acute myeloid leukaemias (AML) and chondrosarcomas, and share a novel …
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Both genome-wide genetic and epigenetic alterations are fundamentally important for the
development of cancers, but the interdependence of these aberrations is poorly understood. …
development of cancers, but the interdependence of these aberrations is poorly understood. …
Satellite-to-ground quantum key distribution
Quantum key distribution (QKD) uses individual light quanta in quantum superposition states
to guarantee unconditional communication security between distant parties. However, the …
to guarantee unconditional communication security between distant parties. However, the …
OPLS4: Improving force field accuracy on challenging regimes of chemical space
We report on the development and validation of the OPLS4 force field. OPLS4 builds upon
our previous work with OPLS3e to improve model accuracy on challenging regimes of drug-…
our previous work with OPLS3e to improve model accuracy on challenging regimes of drug-…
Satellite-based entanglement distribution over 1200 kilometers
Long-distance entanglement distribution is essential for both foundational tests of quantum
physics and scalable quantum networks. Owing to channel loss, however, the previously …
physics and scalable quantum networks. Owing to channel loss, however, the previously …
Multiphoton entanglement and interferometry
Multiphoton interference reveals strictly nonclassical phenomena. Its applications range
from fundamental tests of quantum mechanics to photonic quantum information processing, …
from fundamental tests of quantum mechanics to photonic quantum information processing, …