User profiles for Cezmi Akdis

Cezmi Akdis

University Zurich, Swiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland
Verified email at siaf.uzh.ch
Cited by 97606

Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases

M Akdis, S Burgler, R Crameri, T Eiwegger… - Journal of allergy and …, 2011 - Elsevier
Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections could …

IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy

M Jutel, M Akdis, F Budak… - European journal of …, 2003 - Wiley Online Library
The regulation of normal and allergic immune responses to airborne allergens in the
mucosa is still poorly understood, and the mechanism of specific immunotherapy (SIT) in …

Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells

M Akdis, J Verhagen, A Taylor, F Karamloo… - The Journal of …, 2004 - rupress.org
The mechanisms by which immune responses to nonpathogenic environmental antigens
lead to either allergy or nonharmful immunity are unknown. Single allergen-specific T cells …

Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma …

CA Akdis, M Akdis, T Bieber, C Bindslev-Jensen… - Journal of Allergy and …, 2006 - Elsevier
There are remarkable differences in the diagnostic and therapeutic management of atopic
dermatitis practiced by dermatologists and pediatricians in different countries. Therefore, the …

Type 2 immunity in the skin and lungs

CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular mechanisms
of inflammation and immune regulation in allergic diseases of the skin and lungs during …

Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China

…, X Dong, Y Cao, Y Yuan, Y Yang, Y Yan, CA Akdis… - Allergy, 2020 - Wiley Online Library
Background Coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) infection has been widely spread. We aim to …

Immunological mechanisms of allergen-specific immunotherapy

M Larché, CA Akdis, R Valenta - Nature Reviews Immunology, 2006 - nature.com
Allergen-specific immunotherapy has been carried out for almost a century and remains one
of the few antigen-specific treatments for inflammatory diseases. The mechanisms by which …

Role of interleukin 10 in specific immunotherapy.

CA Akdis, T Blesken, M Akdis… - The Journal of …, 1998 - Am Soc Clin Investig
The induction of allergen-specific anergy in peripheral T cells represents a key step in specific
immunotherapy (SIT). Here we demonstrate that the anergic state results from increased IL…

Risk factors for severe and critically ill COVID‐19 patients: a review

…, W van de Veen, M Sokolowska, M Akdis, CA Akdis - Allergy, 2021 - Wiley Online Library
The pandemic of coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented global social …

Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
As a zoonotic disease that has already spread globally to several million human beings and
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …