[HTML][HTML] Differential regulation of neurotrophin expression in human bronchial smooth muscle cells

C Kemi, J Grunewald, A Eklund, C Olgart Höglund - Respiratory research, 2006 - Springer
Background Human bronchial smooth muscle cells (HBSMC) may regulate airway inflammation
by secreting cytokines, chemokines and growth factors. The neurotrophins, including …

Comparison of aerosol and intranasal challenge in a mouse model of allergic airway inflammation and hyperresponsiveness

L Swedin, R Ellis, C Kemi, Å Ryrfeldt, M Inman… - International archives of …, 2010 - karger.com
Background: The aim was to optimize antigen challenge for induction of airway
hyperresponsiveness (AHR) and inflammation in BALB/c mice sensitized to ovalbumin (OVA). …

Effects of neurotrophins on human bronchial smooth muscle cell migration and matrix metalloproteinase-9 secretion

C Dagnell, C Kemi, J Klominek, P Eriksson… - Translational …, 2007 - Elsevier
The neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF),
and neurotrophin-3 (NT-3) have been found to be upregulated in inflammatory pulmonary …

Mesoporous silica particles potentiate antigen-specific T-cell responses

N Kupferschmidt, KR Qazi, C Kemi, H Vallhov… - …, 2014 - Future Medicine
Aim: To study the adjuvant effect of mesoporous silica particles and their capability of
modifying an already existing allergic Th2-like immune response. Materials & methods: The …

Covalent coupling of vitamin D3 to the major cat allergen Fel d 1 improves the effects of allergen-specific immunotherapy in a mouse model for cat allergy

J Grundström, T Neimert-Andersson, C Kemi… - International archives of …, 2012 - karger.com
Background: Allergen-specific immunotherapy (SIT) is currently the only curative treatment
for allergy but the treatment needs to be improved. We hypothesize that covalent coupling of …

Keeping the blood flowing—plasminogen activator genes and feeding behavior in vampire bats

Å Tellgren-Roth, K Dittmar, SE Massey, C Kemi… - …, 2009 - Springer
The blood feeding vampire bats emerged from New World leaf-nosed bats that fed on fruit
and insects. Plasminogen activator, a serine protease that regulates blood coagulation, is …

Development of a mouse model for chronic cat allergen-induced asthma

J Grundström, T Saarne, C Kemi, JA Gregory… - International archives of …, 2015 - karger.com
Background: Allergic asthma is a chronic inflammatory airway disease caused by exposure
to airborne allergens. In order to develop novel therapies for allergic asthma, models that are …

Effects of tiotropium bromide on airway hyperresponsiveness and inflammation in mice exposed to organic dust

JA Gregory, C Kemi, J Ji, J Karén, I Delin… - Pulmonary …, 2018 - Elsevier
Introduction Acute exposure to organic dust (OD) in pig barns induces intense airway
inflammation with neutrophilia and hyperresponsiveness. This reaction is likely associated with …

[BOOK][B] Studies on neuroimmune interactions in allergic inflammation with focus on neurotrophins

C Kemi - 2006 - search.proquest.com
Allergic asthma is a chronic airway disease characterized by an eosinophilic inflammation,
bronchoconstriction, increased mucus production and bronchial hyperreactivity. The disease …

Effect of dietary nitrite and nitrated fatty acids on airway hyperresponsiveness and inflammation in a mouse model of asthma

C Kemi, S Borniquel, J Lundberg, M Adner, SE Dahlén - 2011 - Eur Respiratory Soc
Dietary nitrite (DN) generates NO that lowers blood pressure in vivo. Nitrated fatty acids (NO
2 -FAs) are formed endogenously from NO and nitrite and display broad anti-inflammatory …