Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …

Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

Background Use of cell-based medicinal products (CBMPs) represents a state-of-the-art
approach for reducing general immunosuppression in organ transplantation. We tested multiple …

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI),
implicating pathways related to neuronal biology. Most GWAS loci represent clusters of …

Identification of genetic risk factors for albuminuria may alter strategies for early prevention
of CKD progression, particularly among patients with diabetes. Little is known about the …

Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD)
and end stage renal disease (ESRD). Previously, we identified 16 loci for eGFR in genome-…

Chronic kidney disease (CKD) is an important public health problem with a genetic component.
We performed genome-wide association studies in up to 130,600 European ancestry …

Aims Patients with chronic heart failure are often characterized by impaired renal function,
also referred to as cardiorenal syndrome (CRS). The aim of this study was to assess whether …

Elevated concentrations of albumin in the urine, albuminuria, are a hallmark of diabetic
kidney disease and are associated with an increased risk for end-stage renal disease and …

Genome-wide association studies (GWASs) have identified multiple loci associated with
cross-sectional eGFR, but a systematic genetic analysis of kidney function decline over time is …