The fission yeast clade—comprising Schizosaccharomyces pombe, S. octosporus, S. cryophilus,
and S. japonicus—occupies the basal branch of Ascomycete fungi and is an important …

Point-of-care testing (POCT) is a laboratory-medicine discipline that is evolving rapidly in
analytical scope and clinical application. In this review, we first describe the state of the art of …

Glioblastoma multiforme (GBM) is the most frequent and aggressive brain tumor in adults.
The dogma that GBM spread is restricted to the brain was challenged by reports on …

INTRODUCTION Although much effort has been devoted to studying yeast in the past few
decades, our understanding of this model organism is still limited. Rapidly developing DNA …

OriDB ( http://www.oridb.org/ ) is a database containing collated genome-wide mapping
studies of confirmed and predicted replication origin sites. The original database collated and …

Three eukaryotic DNA polymerases are essential for genome replication. Polymerase (Pol)
α–primase initiates each synthesis event and is rapidly replaced by processive DNA …

Centromeres play several important roles in ensuring proper chromosome segregation. Not
only do they promote kinetochore assembly for microtubule attachment, but they also …

Biodiversity, a multidimensional property of natural systems, is difficult to quantify partly
because of the multitude of indices proposed for this purpose. Indices aim to describe general …

Eukaryotic genomes are replicated from multiple DNA replication origins. We present
complementary deep sequencing approaches to measure origin location and activity in …

The surface of the primary aerial parts of terrestrial plants is covered by a cuticle, which has
crucial autecological functions, but also serves as an important interface in trophic …