Goblet-cell hyperplasia is a critical pathological feature in hypersecretory diseases of airways.
However, the underlying mechanisms are unknown, and no effective therapy exists. Here …

Background: Antibiotics are commonly prescribed in exacerbations of chronic obstructive
pulmonary disease (COPD). However, the role of bacteria in these exacerbations is …

In patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) needing
hospitalisation, sputum purulence is associated with bacteria in the lower respiratory tract…

Background Assessment of patients with suspected interstitial lung disease (ILD) includes
surgical lung biopsy (SLB) when clinical and radiological data are inconclusive. However, …

The Endobronchial Valve for Emphysema Palliation Trial (VENT) was a multi-centre,
prospective, randomised, controlled trial conducted to evaluate the safety and effectiveness of …

Background: Glucocorticoid treatment alters immunoregulatory defense mechanisms and
may therefore favor the development of different pulmonary infections. Methods: The etiology, …

Study objectives To assess the outcome and the prognostic factors in 200 non-HIV
immunocompromised patients with pulmonary infiltrates (PIs). Design Prospective observational …

Simple Summary Endobronchial-ultrasound transbronchial needle aspiration (EBUS-TBNA)
is essential in the diagnosis and staging of NSCLC, but its usefulness for a full molecular …

We examined the effect of the neutrophil chemoattractants interleukin (IL)-8 andN-formyl-methionyl-leucyl-phenylalanine
on goblet cell (GC) degranulation in guinea pigs. …

Objective: To study the incidence, etiology, and outcome of pulmonary infiltrates (PIs) in HIV-infected
patients and to evaluate the yield of diagnostic procedures. Design: Prospective …