[HTML][HTML] Rapid molecular detection of tuberculosis and rifampin resistance

…, E Gotuzzo, C Rodrigues… - … England Journal of …, 2010 - Mass Medical Soc
Background Global control of tuberculosis is hampered by slow, insensitive diagnostic
methods, particularly for the detection of drug-resistant forms and in patients with human …

Totally drug-resistant tuberculosis in India

…, RA Amale, KK Ajbani, C Rodrigues - Clinical Infectious …, 2012 - academic.oup.com
Abbreviations: gyrA, gyrase subunit A; inhA, enoyl subunit A; katG, catalase peroxidise gene;
rpob, RNA polymerase b subunit; rrs, 16S ribosomal RNA. a The first-and second-line …

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

…, GKH Siu, JG Pasipanodya, C Rodrigues… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis
remains out of control in several parts of the world including Africa and Asia. Although …

[HTML][HTML] Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

…, W Stevens, L Scott, C Rodrigues… - The Lancet infectious …, 2018 - thelancet.com
Background The Xpert MTB/RIF assay is an automated molecular test that has improved the
detection of tuberculosis and rifampicin resistance, but its sensitivity is inadequate in …

The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

…, SG Schumacher, P Nabeta, N Tukvadze, C Rodrigues… - MBio, 2017 - Am Soc Microbiol
The Xpert MTB/RIF assay (Xpert) is a rapid test for tuberculosis (TB) and rifampin resistance
(RIF-R) suitable for point-of-care testing. However, it has decreased sensitivity in smear-…

Enumeration of T Cells Specific for RD1-Encoded Antigens Suggests a High Prevalence of Latent Mycobacterium tuberculosis Infection in Healthy Urban Indians

…, K Ewer, AVS Hill, A Mehta, C Rodrigues - The Journal of …, 2001 - academic.oup.com
Abstract Knowledge of the prevalence of latent Mycobacterium tuberculosis infection is crucial
for effective tuberculosis control, but tuberculin skin test surveys have major limitations, …

Xpert MTB/RIF: a new pillar in diagnosis of extrapulmonary tuberculosis?

…, A Shetty, D Alland, C Rodrigues - Journal of clinical …, 2011 - Am Soc Microbiol
Approximately 10 to 15% of tuberculosis (TB) cases in India are estimated to have
extrapulmonary disease, and due to a lack of diagnostic means, they often remain untreated. The …

[HTML][HTML] Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern

…, A Kagal, A Kapil, R Rao, C Rodrigues… - Indian Journal of …, 2013 - journals.lww.com
Methods: All S. aureus isolates obtained during the study period in the participating centres
were included in the study. Each centre compiled their data in a predefined template which …

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis

…, S Gagneux, S Hoffner, C Rodrigues… - European …, 2017 - Eur Respiratory Soc
A clear understanding of the genetic basis of antibiotic resistance in Mycobacterium tuberculosis
is required to accelerate the development of rapid drug susceptibility testing methods …

[HTML][HTML] The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

…, B Javid, B Zhu, B Letcher, C Rodrigues… - The Lancet …, 2022 - thelancet.com
Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC…