HISTORICAL PERSPECTIVE, PATHOPHYSIOLOGY AND BACTERIOLOGY OF PLEURAL
INFECTION This section provides background information for reference, interest and to set …

Background Intrapleural fibrinolytic agents are used in the drainage of infected pleural-fluid
collections. This use is based on small trials that did not have the statistical power to …

Background More than 30% of patients with pleural infection either die or require surgery.
Drainage of infected fluid is key to successful treatment, but intrapleural fibrinolytic therapy did …

… Davies reported serving on the speakers' bureau for AstraZeneca. Dr Lee reported receiving
honoraria from CareFusion and Sequana Medical as an advisory board member. Dr Miller …

… Davies et al 7 studied 157 patients with confirmed PE who were discharged early from
hospital on LMWH. The median time to diagnosis was 1.0 (range 0–3; 95% CI 0 to 1) days. The …

… Robert JO Davies … Congleton (Worthing Hospital); DC Currie (Dewsbury & District
Hospital); RJO Davies (Oxford Radcliffe Hospital); CWH Davies (The Royal Berkshire Hospital, …

BACKGROUND There is considerable debate regarding the relationship between obstructive
sleep apnoea (OSA) and hypertension. It is unclear whether OSA is an independent …

In pleural infection, medical treatment failure (chest-tube drainage and antibiotics) requires
surgery and increases mortality. It would be helpful to predict which patients will fail this …

AIM: Imaging of pleural empyema by ultrasound (US) or computed tomography (CT) is used
to confirm the diagnosis and facilitate drainage. However, the information gained from US …

… the following conflicts of interest: Dr RJO Davies is funded by the Oxford NIHR Biomedical
Research Centre programme. Dr CWH Davies is an adviser to Smiths Medical and has …