In obese people, the presence of adipose tissue around the rib cage and abdomen and in
the visceral cavity loads the chest wall and reduces functional residual capacity (FRC). The …

The obese asthma phenotype is an increasingly common encounter in our clinical practice.
Epidemiological data indicate that obesity increases the prevalence and incidence of asthma…

Airway hyperresponsiveness (AHR) is a fundamental abnormality in asthma. There are many
potential factors contributing to the excessive airway response demonstrable on airway …

BACKGROUND A study was undertaken to assess whether the recent increases in
prevalence of both asthma and obesity are linked and to determine if obesity is a risk factor for …

… Peat JK, Salome CM, Woolcock AJ. Factors associated with bronchial hyperresponsiveness
in … Haby MM, Peat JK, Mellis CM, et al. An exercise challenge for epidemiological studies of …

In order to determine the shape of the dose-response curves of the human airways to
bronchial challenge, changes in forced expiratory volume in one second (FEV 1 ) after inhaled …

Rationale: The developed world is currently facing an epidemic of obesity. With the increased
prevalence of obesity has come the recognition that obesity is a risk factor for asthma. …

… The exhaled flow, measured by a rotameter (Dwyer Flowmeter Model VFASS-25; AMBIT
Instruments Pty Ltd, Parramatta, Australia), was 10 L/min at a mouth pressure > 20 cm H 2 O. …

Because there Is no" gold standard" for defining asthma for epidemiology, we have defined
current asthma as bronchial hyperresponslveness (BHR) plus recent wheeze (In the …

Background: Obesity may be associated with an increase in asthma and atopy in children. If
so, the effect could be due to an effect of obesity on lung volume and thus airway …