The diagnosis of pleural tuberculosis (plTB) by the analysis of pleural effusions (PEs) with
standard diagnostic tools is difficult. In routine clinical practice, the present authors evaluated …

Rationale: In a large proportion of patients with active pulmonary tuberculosis (pTB), acid-fast
bacilli smear results for sputum and bronchial secretions are negative. Detectable growth …

… , Ernst M, Kalsdorf B, Greinert U, Diel R, Kirsten D, Marienfeld K, Lalvani A, Lange C.
Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked …

Lymphocytes are crucial in the immune defence against Mycobacterium tuberculosis (MTB)
infection. The aim of the present study was to ascertain whether or not MTB-specific …

Immunocompromised patients with acid-fast bacilli (AFB) smear-negative active pulmonary
tuberculosis (pTB) often present with nonspecific clinical symptoms and findings. T-cell …

… quantification of interferon-c production by PBMCs following … test that measures interferon-c
production following antigen … fication of single interferon-c producing cells on the bottom of a …

… (c) Ground truth speckle contrast image for point source illumination 1. Speckle contrast
images were generated for each of the illumination points shown in Fig. 1, resulting in four …

… C. Lange has received personal fees for sponsor-independent lectures at sponsored
symposia from Chiesi, Gilead, Abbvie, MSD, Becton Dickinson, Janssen, Lucane, Novartis and …

Introduction: Sarcoidosis is a multisystem granulomatous disease of unknown origin.
Pathogenetic involvement of Mycobacterium tuberculosis has frequently been discussed in the …

SETTING: The rapid diagnosis of pulmonary tuberculosis (TB) can be challenging if acid-fast
bacilli are not detected by sputum smear microscopy.OBJECTIVE: To compare the results …